Functionalized Gold Nanorods for Tumor Imaging and Targeted Therapy

Gold nanorods, as an emerging noble metal nanomaterial with unique properties, have become the new exciting focus of theoretical and experimental studies in the past few years. The structure and function of gold nanorods, especially their biocompatibility, optical property, and photothermal effects,...

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Main Authors: Chen Gui, Da-xiang Cui
Format: Article
Language:English
Published: China Anti-Cancer Association 2012-12-01
Series:Cancer Biology & Medicine
Subjects:
Online Access:http://www.cancerbiomed.org/index.php/cocr/article/view/368
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author Chen Gui
Da-xiang Cui
author_facet Chen Gui
Da-xiang Cui
author_sort Chen Gui
collection DOAJ
description Gold nanorods, as an emerging noble metal nanomaterial with unique properties, have become the new exciting focus of theoretical and experimental studies in the past few years. The structure and function of gold nanorods, especially their biocompatibility, optical property, and photothermal effects, have been attracting more and more attention. Gold nanorods exhibit great potential in applications such as tumor molecular imaging and photothermal therapy. In this article, we review some of the main advances made over the past few years in the application of gold nanorods in surface functionalization, molecular imaging, and photothermal therapy. We also explore other prospective applications and discuss the corresponding concepts, issues, approaches, and challenges, with the aim of stimulating broader interest in gold nanorod-based nanotechnology and improving its practical application.
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spelling doaj.art-a2eab71daa1d48cf901a66952918e7ff2022-12-22T01:10:46ZengChina Anti-Cancer AssociationCancer Biology & Medicine2095-39412095-39412012-12-019422123310.3969/j.issn.2095-3941.2012.04.0022012040002Functionalized Gold Nanorods for Tumor Imaging and Targeted TherapyChen Gui0Da-xiang Cui1Department of Bio-Nano Science and Engineering, Key Laboratory for Thin Film and Microfabrication of the Ministry of Education, Institute of Micro-Nano Science and Technology, Shanghai Jiaotong University, Shanghai 200240, ChinaDepartment of Bio-Nano Science and Engineering, Key Laboratory for Thin Film and Microfabrication of the Ministry of Education, Institute of Micro-Nano Science and Technology, Shanghai Jiaotong University, Shanghai 200240, ChinaGold nanorods, as an emerging noble metal nanomaterial with unique properties, have become the new exciting focus of theoretical and experimental studies in the past few years. The structure and function of gold nanorods, especially their biocompatibility, optical property, and photothermal effects, have been attracting more and more attention. Gold nanorods exhibit great potential in applications such as tumor molecular imaging and photothermal therapy. In this article, we review some of the main advances made over the past few years in the application of gold nanorods in surface functionalization, molecular imaging, and photothermal therapy. We also explore other prospective applications and discuss the corresponding concepts, issues, approaches, and challenges, with the aim of stimulating broader interest in gold nanorod-based nanotechnology and improving its practical application.http://www.cancerbiomed.org/index.php/cocr/article/view/368gold nanorodssurface functionalizationtumormolecular imagingphotothermal therapy
spellingShingle Chen Gui
Da-xiang Cui
Functionalized Gold Nanorods for Tumor Imaging and Targeted Therapy
Cancer Biology & Medicine
gold nanorods
surface functionalization
tumor
molecular imaging
photothermal therapy
title Functionalized Gold Nanorods for Tumor Imaging and Targeted Therapy
title_full Functionalized Gold Nanorods for Tumor Imaging and Targeted Therapy
title_fullStr Functionalized Gold Nanorods for Tumor Imaging and Targeted Therapy
title_full_unstemmed Functionalized Gold Nanorods for Tumor Imaging and Targeted Therapy
title_short Functionalized Gold Nanorods for Tumor Imaging and Targeted Therapy
title_sort functionalized gold nanorods for tumor imaging and targeted therapy
topic gold nanorods
surface functionalization
tumor
molecular imaging
photothermal therapy
url http://www.cancerbiomed.org/index.php/cocr/article/view/368
work_keys_str_mv AT chengui functionalizedgoldnanorodsfortumorimagingandtargetedtherapy
AT daxiangcui functionalizedgoldnanorodsfortumorimagingandtargetedtherapy