Fibroblast and keratinocyte gene expression following exposure to extracts of neem plant (Azadirachta indica)
This data article provides gene expression profiles, determined by using real-time PCR, of fibroblasts and keratinocytes treated with 0.01% and 0.001% extracts of neem plant (Azadirachta indica), local name “Kohomba” in Sri Lanka, harvested in Sri Lanka. For fibroblasts, the dataset includes express...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2018-02-01
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| Series: | Data in Brief |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2352340917307308 |
| _version_ | 1811203158214443008 |
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| author | Takao Someya Katsura Sano Kotaro Hara Yoshimasa Sagane Toshihiro Watanabe R.G.S. Wijesekara |
| author_facet | Takao Someya Katsura Sano Kotaro Hara Yoshimasa Sagane Toshihiro Watanabe R.G.S. Wijesekara |
| author_sort | Takao Someya |
| collection | DOAJ |
| description | This data article provides gene expression profiles, determined by using real-time PCR, of fibroblasts and keratinocytes treated with 0.01% and 0.001% extracts of neem plant (Azadirachta indica), local name “Kohomba” in Sri Lanka, harvested in Sri Lanka. For fibroblasts, the dataset includes expression profiles for genes encoding hyaluronan synthase 1 (HAS1), hyaluronan synthase 2 (HAS2), hyaluronidase-1 (HYAL1), hyaluronidase-2 (HYAL2), versican, aggrecan, CD44, collagen, type I, alpha 1 (COL1A1), collagen, type III, alpha 1 (COL3A1), collagen, type VII, alpha 1 (COL7A1), matrix metalloproteinase 1 (MMP1), acid ceramidase, basic fibroblast growth factor (bFGF), fibroblast growth factor-7 (FGF7), vascular endothelial growth factor (VEGF), interleukin-1 alpha (IL-1α), cyclooxygenase-2 (cox2), transforming growth factor beta (TGF-β), and aquaporin 3 (AQP3). For keratinocytes, the expression profiles are for genes encoding HAS1, HAS2, HYAL1, HYAL2, versican, CD44, IL-1α, cox2, TGF-β, AQP3, Laminin5, collagen, type XVII, alpha 1 (COL17A1), integrin alpha-6 (ITGA6), ceramide synthase 3 (CERS3), elongation of very long chain fatty acids protein 1 (ELOVL1), elongation of very long chain fatty acids protein 4 (ELOVL4), filaggrin (FLG), transglutaminase 1 (TGM1), and keratin 1 (KRT1). The expression profiles are provided as bar graphs. Keywords: Real-time PCR, Gene expression profile, Fibroblast, Keratinocyte, Neem extract, Azadirachta indica, Kohomba |
| first_indexed | 2024-04-12T02:49:47Z |
| format | Article |
| id | doaj.art-a2eec5727fec413e88c067ec8a29fa80 |
| institution | Directory Open Access Journal |
| issn | 2352-3409 |
| language | English |
| last_indexed | 2024-04-12T02:49:47Z |
| publishDate | 2018-02-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Data in Brief |
| spelling | doaj.art-a2eec5727fec413e88c067ec8a29fa802022-12-22T03:51:01ZengElsevierData in Brief2352-34092018-02-0116982992Fibroblast and keratinocyte gene expression following exposure to extracts of neem plant (Azadirachta indica)Takao Someya0Katsura Sano1Kotaro Hara2Yoshimasa Sagane3Toshihiro Watanabe4R.G.S. Wijesekara5ALBION Co. Ltd., 1–7-10 Ginza, Chuo-ku, Tokyo 104-0061, Japan; Corresponding author.ALBION Co. Ltd., 1–7-10 Ginza, Chuo-ku, Tokyo 104-0061, JapanALBION Co. Ltd., 1–7-10 Ginza, Chuo-ku, Tokyo 104-0061, JapanDepartment of food and Cosmetic Science, Faculty of Bioindustry, Tokyo University of Agriculture, 196 Yasaka, Abashiri, Hokkaido 099–2493, JapanDepartment of food and Cosmetic Science, Faculty of Bioindustry, Tokyo University of Agriculture, 196 Yasaka, Abashiri, Hokkaido 099–2493, JapanDepartment of Aquaculture and Fisheries, Faculty of Livestock, Fisheries and Nutrition, Wayamba University of Sri Lanka, Makandura, Gonawila 60170, Sri LankaThis data article provides gene expression profiles, determined by using real-time PCR, of fibroblasts and keratinocytes treated with 0.01% and 0.001% extracts of neem plant (Azadirachta indica), local name “Kohomba” in Sri Lanka, harvested in Sri Lanka. For fibroblasts, the dataset includes expression profiles for genes encoding hyaluronan synthase 1 (HAS1), hyaluronan synthase 2 (HAS2), hyaluronidase-1 (HYAL1), hyaluronidase-2 (HYAL2), versican, aggrecan, CD44, collagen, type I, alpha 1 (COL1A1), collagen, type III, alpha 1 (COL3A1), collagen, type VII, alpha 1 (COL7A1), matrix metalloproteinase 1 (MMP1), acid ceramidase, basic fibroblast growth factor (bFGF), fibroblast growth factor-7 (FGF7), vascular endothelial growth factor (VEGF), interleukin-1 alpha (IL-1α), cyclooxygenase-2 (cox2), transforming growth factor beta (TGF-β), and aquaporin 3 (AQP3). For keratinocytes, the expression profiles are for genes encoding HAS1, HAS2, HYAL1, HYAL2, versican, CD44, IL-1α, cox2, TGF-β, AQP3, Laminin5, collagen, type XVII, alpha 1 (COL17A1), integrin alpha-6 (ITGA6), ceramide synthase 3 (CERS3), elongation of very long chain fatty acids protein 1 (ELOVL1), elongation of very long chain fatty acids protein 4 (ELOVL4), filaggrin (FLG), transglutaminase 1 (TGM1), and keratin 1 (KRT1). The expression profiles are provided as bar graphs. Keywords: Real-time PCR, Gene expression profile, Fibroblast, Keratinocyte, Neem extract, Azadirachta indica, Kohombahttp://www.sciencedirect.com/science/article/pii/S2352340917307308 |
| spellingShingle | Takao Someya Katsura Sano Kotaro Hara Yoshimasa Sagane Toshihiro Watanabe R.G.S. Wijesekara Fibroblast and keratinocyte gene expression following exposure to extracts of neem plant (Azadirachta indica) Data in Brief |
| title | Fibroblast and keratinocyte gene expression following exposure to extracts of neem plant (Azadirachta indica) |
| title_full | Fibroblast and keratinocyte gene expression following exposure to extracts of neem plant (Azadirachta indica) |
| title_fullStr | Fibroblast and keratinocyte gene expression following exposure to extracts of neem plant (Azadirachta indica) |
| title_full_unstemmed | Fibroblast and keratinocyte gene expression following exposure to extracts of neem plant (Azadirachta indica) |
| title_short | Fibroblast and keratinocyte gene expression following exposure to extracts of neem plant (Azadirachta indica) |
| title_sort | fibroblast and keratinocyte gene expression following exposure to extracts of neem plant azadirachta indica |
| url | http://www.sciencedirect.com/science/article/pii/S2352340917307308 |
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