Skeleton keys in the phage world
The viruses infecting bacteria, known as phages, carry a wondrous diversity of enzymes known as endolysins, which are responsible for opening cellular doors, like the membrane or wall, so that newly minted phages are set free. In a recent study, Oechslin and colleagues explored the evolutionary myst...
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2022-11-01
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| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-022-04155-5 |
| _version_ | 1797988416590184448 |
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| author | Melissa Walker |
| author_facet | Melissa Walker |
| author_sort | Melissa Walker |
| collection | DOAJ |
| description | The viruses infecting bacteria, known as phages, carry a wondrous diversity of enzymes known as endolysins, which are responsible for opening cellular doors, like the membrane or wall, so that newly minted phages are set free. In a recent study, Oechslin and colleagues explored the evolutionary mystery of lactococcal endolysin biodiversity, suggesting that these endolysins are flexible and can be used as kinds of skeleton keys to open a broad range of cellular doors. |
| first_indexed | 2024-04-11T08:03:54Z |
| format | Article |
| id | doaj.art-a2eede23a3c64f2e88820f59675871e3 |
| institution | Directory Open Access Journal |
| issn | 2399-3642 |
| language | English |
| last_indexed | 2024-04-11T08:03:54Z |
| publishDate | 2022-11-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Communications Biology |
| spelling | doaj.art-a2eede23a3c64f2e88820f59675871e32022-12-22T04:35:37ZengNature PortfolioCommunications Biology2399-36422022-11-01511210.1038/s42003-022-04155-5Skeleton keys in the phage worldMelissa Walker0Department of Biology, University of Alabama at BirminghamThe viruses infecting bacteria, known as phages, carry a wondrous diversity of enzymes known as endolysins, which are responsible for opening cellular doors, like the membrane or wall, so that newly minted phages are set free. In a recent study, Oechslin and colleagues explored the evolutionary mystery of lactococcal endolysin biodiversity, suggesting that these endolysins are flexible and can be used as kinds of skeleton keys to open a broad range of cellular doors.https://doi.org/10.1038/s42003-022-04155-5 |
| spellingShingle | Melissa Walker Skeleton keys in the phage world Communications Biology |
| title | Skeleton keys in the phage world |
| title_full | Skeleton keys in the phage world |
| title_fullStr | Skeleton keys in the phage world |
| title_full_unstemmed | Skeleton keys in the phage world |
| title_short | Skeleton keys in the phage world |
| title_sort | skeleton keys in the phage world |
| url | https://doi.org/10.1038/s42003-022-04155-5 |
| work_keys_str_mv | AT melissawalker skeletonkeysinthephageworld |