Thioredoxin-1 Ameliorates Oxygen-Induced Retinopathy in Newborn Mice through Modulation of Proinflammatory and Angiogenic Factors

Thioredoxin-1 Ameliorates Oxygen-Induced Retinopathy in Newborn Mice through Modulation of Proinflammatory and Angiogenic Factors

Oxygen-induced retinopathy (OIR) is an animal model for retinopathy of prematurity, which is a leading cause of blindness in children. Thioredoxin-1 (TRX) is a small redox protein that has cytoprotective and anti-inflammatory properties in response to oxidative stress. The purpose of this study was...

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Bibliographic Details
Main Authors: Junichi Ozawa, Kosuke Tanaka, Yukio Arai, Mitsuhiro Haga, Naoyuki Miyahara, Ai Miyamoto, Eri Nishimura, Fumihiko Namba
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Antioxidants
Subjects:
oxygen-induced retinopathy
retinopathy of prematurity
retinal blood vessel
thioredoxin-1
newborn mouse
hyperoxia
Online Access:https://www.mdpi.com/2076-3921/11/5/899

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