Influence of postoperative ectopic inner foveal layer on visual function after removal of idiopathic epiretinal membrane
<h4>Purpose</h4> To investigate the functional and anatomical parameters and their postoperative changes according to the ectopic inner foveal layer (EIFL) staging scheme for idiopathic epiretinal membrane (ERM). <h4>Methods</h4> In this prospective study, patients with idiop...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2021-01-01
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| Series: | PLoS ONE |
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8568108/?tool=EBI |
| _version_ | 1831713065573285888 |
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| author | Bo Hee Kim Dong Ik Kim Ki Woong Bae Un Chul Park |
| author_facet | Bo Hee Kim Dong Ik Kim Ki Woong Bae Un Chul Park |
| author_sort | Bo Hee Kim |
| collection | DOAJ |
| description | <h4>Purpose</h4> To investigate the functional and anatomical parameters and their postoperative changes according to the ectopic inner foveal layer (EIFL) staging scheme for idiopathic epiretinal membrane (ERM). <h4>Methods</h4> In this prospective study, patients with idiopathic ERM underwent pars plana vitrectomy and ERM removal, and were followed-up for 6 months. The associations of EIFL with pre- and postoperative functional and anatomical parameters were analyzed. <h4>Results</h4> A total of 84 eyes (84 patients) were included: 39 (46.4%), 33 (39.3%), and 12 (14.3%) as EIFL stages 2, 3, and 4, respectively. At 6 months after surgery, the mean best-corrected visual acuity (BCVA) significantly improved in all EIFL stages (P ≤ 0.003); however, metamorphopsia improved only in eyes with EIFL stage 2 (P = 0.039) and 3 (P = 0.011). The aniseikonia and foveal avascular zone (FAZ) area showed no significant postoperative changes in any of the EIFL stages. Both preoperatively and during 6 months after surgery, the EIFL stage showed a significant correlation with BCVA (P ≤ 0.033), metamorphopsia (P ≤ 0.008), central macular thickness (P < 0.001), and FAZ parameters (P ≤ 0.016) at each time point, but not with aniseikonia. Significant correlations of EIFL thickness with BCVA (P = 0.028) and metamorphopsia (P = 0.006) before surgery were not persistent after surgery. <h4>Conclusion</h4> Both pre- and postoperatively, the staging of EIFL, rather than its thickness, is a simple and adequate surrogate marker for visual acuity and metamorphopsia in eyes with idiopathic ERM. |
| first_indexed | 2024-12-20T23:34:25Z |
| format | Article |
| id | doaj.art-a2f3780a9b4641959c733902347b3092 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-20T23:34:25Z |
| publishDate | 2021-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-a2f3780a9b4641959c733902347b30922022-12-21T19:23:14ZengPublic Library of Science (PLoS)PLoS ONE1932-62032021-01-011611Influence of postoperative ectopic inner foveal layer on visual function after removal of idiopathic epiretinal membraneBo Hee KimDong Ik KimKi Woong BaeUn Chul Park<h4>Purpose</h4> To investigate the functional and anatomical parameters and their postoperative changes according to the ectopic inner foveal layer (EIFL) staging scheme for idiopathic epiretinal membrane (ERM). <h4>Methods</h4> In this prospective study, patients with idiopathic ERM underwent pars plana vitrectomy and ERM removal, and were followed-up for 6 months. The associations of EIFL with pre- and postoperative functional and anatomical parameters were analyzed. <h4>Results</h4> A total of 84 eyes (84 patients) were included: 39 (46.4%), 33 (39.3%), and 12 (14.3%) as EIFL stages 2, 3, and 4, respectively. At 6 months after surgery, the mean best-corrected visual acuity (BCVA) significantly improved in all EIFL stages (P ≤ 0.003); however, metamorphopsia improved only in eyes with EIFL stage 2 (P = 0.039) and 3 (P = 0.011). The aniseikonia and foveal avascular zone (FAZ) area showed no significant postoperative changes in any of the EIFL stages. Both preoperatively and during 6 months after surgery, the EIFL stage showed a significant correlation with BCVA (P ≤ 0.033), metamorphopsia (P ≤ 0.008), central macular thickness (P < 0.001), and FAZ parameters (P ≤ 0.016) at each time point, but not with aniseikonia. Significant correlations of EIFL thickness with BCVA (P = 0.028) and metamorphopsia (P = 0.006) before surgery were not persistent after surgery. <h4>Conclusion</h4> Both pre- and postoperatively, the staging of EIFL, rather than its thickness, is a simple and adequate surrogate marker for visual acuity and metamorphopsia in eyes with idiopathic ERM.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8568108/?tool=EBI |
| spellingShingle | Bo Hee Kim Dong Ik Kim Ki Woong Bae Un Chul Park Influence of postoperative ectopic inner foveal layer on visual function after removal of idiopathic epiretinal membrane PLoS ONE |
| title | Influence of postoperative ectopic inner foveal layer on visual function after removal of idiopathic epiretinal membrane |
| title_full | Influence of postoperative ectopic inner foveal layer on visual function after removal of idiopathic epiretinal membrane |
| title_fullStr | Influence of postoperative ectopic inner foveal layer on visual function after removal of idiopathic epiretinal membrane |
| title_full_unstemmed | Influence of postoperative ectopic inner foveal layer on visual function after removal of idiopathic epiretinal membrane |
| title_short | Influence of postoperative ectopic inner foveal layer on visual function after removal of idiopathic epiretinal membrane |
| title_sort | influence of postoperative ectopic inner foveal layer on visual function after removal of idiopathic epiretinal membrane |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8568108/?tool=EBI |
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