Validation of the Simplified UVB Model to Assess the Pharmacodynamics of Analgesics in Healthy Human Volunteers

Validation of the Simplified UVB Model to Assess the Pharmacodynamics of Analgesics in Healthy Human Volunteers

A pharmacokinetic/pharmacodynamic, randomized, crossover, placebo-controlled study was conducted in healthy human volunteers with the primary objective of exploring the existence of a positive interaction between paracetamol 1 g and ketorolac 20 mg intravenously on experimental pain models...

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Bibliographic Details
Main Authors: Kuntheavy Ing Lorenzini, Marie Besson, Youssef Daali, Denis Salomon, Pierre Dayer, Jules Desmeules
Format: Article
Language:deu
Published: Swiss Chemical Society 2012-05-01
Series:CHIMIA
Subjects:
Analgesics combination
Nsaids
Paracetamol
Uvb
Variability
Online Access:https://www.chimia.ch/chimia/article/view/5211

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