Hormonal, electrolyte disturbances and features of hemostasis in term newborn infants of mothers with gestational diabetes mellitus.

The article reviews the available data on investigations in the field of electrolyte (calcium, magnesium), hormonal (insulin, leptin) and hemostasis disturbances in term newborns from women with gestational diabetes; possible mechanisms of their development are also highlighted. The review describes...

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Main Authors: Evgeny Viktorovich Mikhalev, Olga Michailovna Shanina, Tatiana Vladimirovna Saprina
Format: Article
Language:English
Published: Endocrinology Research Centre 2015-03-01
Series:Сахарный диабет
Subjects:
Online Access:https://www.dia-endojournals.ru/jour/article/view/6714
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author Evgeny Viktorovich Mikhalev
Olga Michailovna Shanina
Tatiana Vladimirovna Saprina
author_facet Evgeny Viktorovich Mikhalev
Olga Michailovna Shanina
Tatiana Vladimirovna Saprina
author_sort Evgeny Viktorovich Mikhalev
collection DOAJ
description The article reviews the available data on investigations in the field of electrolyte (calcium, magnesium), hormonal (insulin, leptin) and hemostasis disturbances in term newborns from women with gestational diabetes; possible mechanisms of their development are also highlighted. The review describes changes in blood glucose concentration in term newborns from women with gestational diabetes, and their impact on the child's condition. In addition to already known factors causing macrosomia and other metabolic disorders in term neonates, the role of leptin (peptide hormone that regulates energy metabolism) is quite discussable. Low leptin levels lead to the development of obesity. It is also confirmed, that leptin influences brain development of the newborn, leading to later cognitive deficits in children from women with GDM. The aim of the review is to summarize the available data on investigations in the field of electrolyte (calcium, magnesium), hormonal (insulin, leptin) and hemostasis disturbances in term newborns from women with gestational diabetes.
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spelling doaj.art-a2f64254a64b45d09cfb05325f9eacd22024-03-20T11:48:00ZengEndocrinology Research CentreСахарный диабет2072-03512072-03782015-03-01181788610.14341/DM2015178-866562Hormonal, electrolyte disturbances and features of hemostasis in term newborn infants of mothers with gestational diabetes mellitus.Evgeny Viktorovich Mikhalev0Olga Michailovna Shanina1Tatiana Vladimirovna Saprina2Siberian State Medical University, TomskSiberian State Medical University, TomskSiberian State Medical University, TomskThe article reviews the available data on investigations in the field of electrolyte (calcium, magnesium), hormonal (insulin, leptin) and hemostasis disturbances in term newborns from women with gestational diabetes; possible mechanisms of their development are also highlighted. The review describes changes in blood glucose concentration in term newborns from women with gestational diabetes, and their impact on the child's condition. In addition to already known factors causing macrosomia and other metabolic disorders in term neonates, the role of leptin (peptide hormone that regulates energy metabolism) is quite discussable. Low leptin levels lead to the development of obesity. It is also confirmed, that leptin influences brain development of the newborn, leading to later cognitive deficits in children from women with GDM. The aim of the review is to summarize the available data on investigations in the field of electrolyte (calcium, magnesium), hormonal (insulin, leptin) and hemostasis disturbances in term newborns from women with gestational diabetes.https://www.dia-endojournals.ru/jour/article/view/6714term newbornmagnesiumcalciumglucoseleptininsulinhemostasisgestational diabetes
spellingShingle Evgeny Viktorovich Mikhalev
Olga Michailovna Shanina
Tatiana Vladimirovna Saprina
Hormonal, electrolyte disturbances and features of hemostasis in term newborn infants of mothers with gestational diabetes mellitus.
Сахарный диабет
term newborn
magnesium
calcium
glucose
leptin
insulin
hemostasis
gestational diabetes
title Hormonal, electrolyte disturbances and features of hemostasis in term newborn infants of mothers with gestational diabetes mellitus.
title_full Hormonal, electrolyte disturbances and features of hemostasis in term newborn infants of mothers with gestational diabetes mellitus.
title_fullStr Hormonal, electrolyte disturbances and features of hemostasis in term newborn infants of mothers with gestational diabetes mellitus.
title_full_unstemmed Hormonal, electrolyte disturbances and features of hemostasis in term newborn infants of mothers with gestational diabetes mellitus.
title_short Hormonal, electrolyte disturbances and features of hemostasis in term newborn infants of mothers with gestational diabetes mellitus.
title_sort hormonal electrolyte disturbances and features of hemostasis in term newborn infants of mothers with gestational diabetes mellitus
topic term newborn
magnesium
calcium
glucose
leptin
insulin
hemostasis
gestational diabetes
url https://www.dia-endojournals.ru/jour/article/view/6714
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AT olgamichailovnashanina hormonalelectrolytedisturbancesandfeaturesofhemostasisintermnewborninfantsofmotherswithgestationaldiabetesmellitus
AT tatianavladimirovnasaprina hormonalelectrolytedisturbancesandfeaturesofhemostasisintermnewborninfantsofmotherswithgestationaldiabetesmellitus