Time-series analysis of the association between air pollution exposure and outpatient visits for dry eye disease: a case study in Zhengzhou, China
BackgroundDry eye disease (DED) is a prevalent ocular surface disease that significantly impacts patients’ quality of life. The association between air pollution and the risk of dry eye disease remains uncertain.MethodsData on outdoor air pollutants, meteorological information, and outpatient visits...
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Frontiers Media S.A.
2024-03-01
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| Series: | Frontiers in Public Health |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fpubh.2024.1352057/full |
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| author | Mengting Xia Yingrui Yang Jiali Sun Ranran Huang Yonghui Huang Mengqi Zhang Xi Yao |
| author_facet | Mengting Xia Yingrui Yang Jiali Sun Ranran Huang Yonghui Huang Mengqi Zhang Xi Yao |
| author_sort | Mengting Xia |
| collection | DOAJ |
| description | BackgroundDry eye disease (DED) is a prevalent ocular surface disease that significantly impacts patients’ quality of life. The association between air pollution and the risk of dry eye disease remains uncertain.MethodsData on outdoor air pollutants, meteorological information, and outpatient visits for DED were collected from July 1, 2014, to December 31, 2019. The relationship between ambient air pollutants and DED outpatient visits was analyzed using a generalized additive model with a Poisson distribution.ResultsAmong the 5,204 DED patients included in the study, 63.76% were female and 36.24% were male. The single-pollutant model revealed a significant association between a 10 μg/m3 increase in concentrations of fine-particulate matter with a median aerometric diameter of less than 10 μm (PM10), sulfur dioxide (SO2), nitrogen dioxide (NO2), and carbon monoxide (CO) and outpatient visits for DED. Fine-particulate matter with a median aerometric diameter of less than 2.5 μm (PM2.5) showed a significant association with DED outpatient visits in males and the 19–59 years age group. The strongest associations between air pollutants and outpatient visits were observed in male patients and during the cold season.ConclusionThe noteworthy correlation between air pollutants and DED outpatient visits can offer evidence for policy makers and underscore the significance of reinforcing environmental protection. |
| first_indexed | 2024-04-25T00:07:14Z |
| format | Article |
| id | doaj.art-a2f6911615f2460196827e11da9e5953 |
| institution | Directory Open Access Journal |
| issn | 2296-2565 |
| language | English |
| last_indexed | 2024-04-25T00:07:14Z |
| publishDate | 2024-03-01 |
| publisher | Frontiers Media S.A. |
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| series | Frontiers in Public Health |
| spelling | doaj.art-a2f6911615f2460196827e11da9e59532024-03-14T05:08:20ZengFrontiers Media S.A.Frontiers in Public Health2296-25652024-03-011210.3389/fpubh.2024.13520571352057Time-series analysis of the association between air pollution exposure and outpatient visits for dry eye disease: a case study in Zhengzhou, ChinaMengting Xia0Yingrui Yang1Jiali Sun2Ranran Huang3Yonghui Huang4Mengqi Zhang5Xi Yao6Henan Eye Institute & Henan Eye Hospital, Henan Provincial People’s Hospital, People’s Hospital of Zhengzhou University, Zhengzhou, ChinaHenan Eye Institute & Henan Eye Hospital, Henan Provincial People’s Hospital, People’s Hospital of Zhengzhou University, Zhengzhou, ChinaHenan Eye Institute & Henan Eye Hospital, Henan Provincial People’s Hospital, People’s Hospital of Zhengzhou University, Zhengzhou, ChinaHenan Eye Institute & Henan Eye Hospital, Henan Provincial People’s Hospital, People’s Hospital of Zhengzhou University, Zhengzhou, ChinaHenan Eye Institute & Henan Eye Hospital, Henan Provincial People’s Hospital, People’s Hospital of Zhengzhou University, Zhengzhou, ChinaHospital-Acquired Infection Control Department, School and Hospital of Stomatology, Wenzhou Medical University, Wenzhou, ChinaHenan Eye Institute & Henan Eye Hospital, Henan Provincial People’s Hospital, People’s Hospital of Zhengzhou University, Zhengzhou, ChinaBackgroundDry eye disease (DED) is a prevalent ocular surface disease that significantly impacts patients’ quality of life. The association between air pollution and the risk of dry eye disease remains uncertain.MethodsData on outdoor air pollutants, meteorological information, and outpatient visits for DED were collected from July 1, 2014, to December 31, 2019. The relationship between ambient air pollutants and DED outpatient visits was analyzed using a generalized additive model with a Poisson distribution.ResultsAmong the 5,204 DED patients included in the study, 63.76% were female and 36.24% were male. The single-pollutant model revealed a significant association between a 10 μg/m3 increase in concentrations of fine-particulate matter with a median aerometric diameter of less than 10 μm (PM10), sulfur dioxide (SO2), nitrogen dioxide (NO2), and carbon monoxide (CO) and outpatient visits for DED. Fine-particulate matter with a median aerometric diameter of less than 2.5 μm (PM2.5) showed a significant association with DED outpatient visits in males and the 19–59 years age group. The strongest associations between air pollutants and outpatient visits were observed in male patients and during the cold season.ConclusionThe noteworthy correlation between air pollutants and DED outpatient visits can offer evidence for policy makers and underscore the significance of reinforcing environmental protection.https://www.frontiersin.org/articles/10.3389/fpubh.2024.1352057/fulldry eye diseasegeneralized additive modelair pollutionoutpatient visitsocular surface disease |
| spellingShingle | Mengting Xia Yingrui Yang Jiali Sun Ranran Huang Yonghui Huang Mengqi Zhang Xi Yao Time-series analysis of the association between air pollution exposure and outpatient visits for dry eye disease: a case study in Zhengzhou, China Frontiers in Public Health dry eye disease generalized additive model air pollution outpatient visits ocular surface disease |
| title | Time-series analysis of the association between air pollution exposure and outpatient visits for dry eye disease: a case study in Zhengzhou, China |
| title_full | Time-series analysis of the association between air pollution exposure and outpatient visits for dry eye disease: a case study in Zhengzhou, China |
| title_fullStr | Time-series analysis of the association between air pollution exposure and outpatient visits for dry eye disease: a case study in Zhengzhou, China |
| title_full_unstemmed | Time-series analysis of the association between air pollution exposure and outpatient visits for dry eye disease: a case study in Zhengzhou, China |
| title_short | Time-series analysis of the association between air pollution exposure and outpatient visits for dry eye disease: a case study in Zhengzhou, China |
| title_sort | time series analysis of the association between air pollution exposure and outpatient visits for dry eye disease a case study in zhengzhou china |
| topic | dry eye disease generalized additive model air pollution outpatient visits ocular surface disease |
| url | https://www.frontiersin.org/articles/10.3389/fpubh.2024.1352057/full |
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