Breast cancer metastatic to the pituitary gland: a case report

<p>Abstract</p> <p>Background</p> <p>Metastases to the pituitary gland are rare events, and usually indicate widespread malignant disease. The lung and the breast are the most common sites of primary tumors that metastasize to the pituitary gland.</p> <p>Met...

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Main Authors: Spinelli Gian, Lo Russo Giuseppe, Miele Evelina, Prinzi Natalie, Tomao Federica, Antonelli Manila, Giangaspero Felice, Stati Valeria, Strudel Martina, Tomao Silverio
Format: Article
Language:English
Published: BMC 2012-07-01
Series:World Journal of Surgical Oncology
Subjects:
Online Access:http://www.wjso.com/content/10/1/137
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author Spinelli Gian
Lo Russo Giuseppe
Miele Evelina
Prinzi Natalie
Tomao Federica
Antonelli Manila
Giangaspero Felice
Stati Valeria
Strudel Martina
Tomao Silverio
author_facet Spinelli Gian
Lo Russo Giuseppe
Miele Evelina
Prinzi Natalie
Tomao Federica
Antonelli Manila
Giangaspero Felice
Stati Valeria
Strudel Martina
Tomao Silverio
author_sort Spinelli Gian
collection DOAJ
description <p>Abstract</p> <p>Background</p> <p>Metastases to the pituitary gland are rare events, and usually indicate widespread malignant disease. The lung and the breast are the most common sites of primary tumors that metastasize to the pituitary gland.</p> <p>Metastases are more frequent in older patients and the most common symptoms at presentation are diabetes insipidus and visual alterations.</p> <p>Case presentation</p> <p>72-year-old white woman was treated for a breast carcinoma with right superoexternal quadrantectomy, radiotherapy, and hormone therapy. Twelve years later, the patient presented with bone pain, bilateral progressive visual decline, and onset of hypopituitarism. A diagnosis of secondary bone involvement and pituitary metastasis was made.</p> <p>Conclusion</p> <p>This was an unusual disease course, and stresses the importance of intensive follow-up in patients with breast cancer even many years after the initial diagnosis This case emphasizes that diagnosis can be difficultand controversial when relapse occurs at uncommon sites.</p>
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spelling doaj.art-a2f8b859075c483a8423a396c4ac33792022-12-22T01:19:48ZengBMCWorld Journal of Surgical Oncology1477-78192012-07-0110113710.1186/1477-7819-10-137Breast cancer metastatic to the pituitary gland: a case reportSpinelli GianLo Russo GiuseppeMiele EvelinaPrinzi NatalieTomao FedericaAntonelli ManilaGiangaspero FeliceStati ValeriaStrudel MartinaTomao Silverio<p>Abstract</p> <p>Background</p> <p>Metastases to the pituitary gland are rare events, and usually indicate widespread malignant disease. The lung and the breast are the most common sites of primary tumors that metastasize to the pituitary gland.</p> <p>Metastases are more frequent in older patients and the most common symptoms at presentation are diabetes insipidus and visual alterations.</p> <p>Case presentation</p> <p>72-year-old white woman was treated for a breast carcinoma with right superoexternal quadrantectomy, radiotherapy, and hormone therapy. Twelve years later, the patient presented with bone pain, bilateral progressive visual decline, and onset of hypopituitarism. A diagnosis of secondary bone involvement and pituitary metastasis was made.</p> <p>Conclusion</p> <p>This was an unusual disease course, and stresses the importance of intensive follow-up in patients with breast cancer even many years after the initial diagnosis This case emphasizes that diagnosis can be difficultand controversial when relapse occurs at uncommon sites.</p>http://www.wjso.com/content/10/1/137Breast cancerPituitary metastasesFollow-upControversial diagnosis
spellingShingle Spinelli Gian
Lo Russo Giuseppe
Miele Evelina
Prinzi Natalie
Tomao Federica
Antonelli Manila
Giangaspero Felice
Stati Valeria
Strudel Martina
Tomao Silverio
Breast cancer metastatic to the pituitary gland: a case report
World Journal of Surgical Oncology
Breast cancer
Pituitary metastases
Follow-up
Controversial diagnosis
title Breast cancer metastatic to the pituitary gland: a case report
title_full Breast cancer metastatic to the pituitary gland: a case report
title_fullStr Breast cancer metastatic to the pituitary gland: a case report
title_full_unstemmed Breast cancer metastatic to the pituitary gland: a case report
title_short Breast cancer metastatic to the pituitary gland: a case report
title_sort breast cancer metastatic to the pituitary gland a case report
topic Breast cancer
Pituitary metastases
Follow-up
Controversial diagnosis
url http://www.wjso.com/content/10/1/137
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