Date palm seed extract and herbal mixture mitigate gentamicin-induced renal injury in mice: Role of Protease-activated receptors (PARs) and Retinoid X receptor alpha (RXR-α)

Date palm seed extract and herbal mixture mitigate gentamicin-induced renal injury in mice: Role of Protease-activated receptors (PARs) and Retinoid X receptor alpha (RXR-α)

Introduction: Gentamicin (Gen) causes renal toxicity by inhibiting protein synthesis in kidney cells, causing proximal tubule cell necrosis and renal failure. Herein, we examined the nephroprotective effect of date palm seed extract (DPSE) and one herbal mixture (HM; composed of Tribulus terrestris,...

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Bibliographic Details
Main Authors: Suliman Sohaim, Salman Mohammed, Elham Amin, Hussein M Ali, Mohamed Abdelbakky
Format: Article
Language:English
Published: Shahrekord University of Medical Sciences 2022-04-01
Series:Journal of HerbMed Pharmacology
Subjects:
nephroprotection
renal toxicity
gentamycin
renal injury
histopathology
phoenix dactylifera
Online Access:http://herbmedpharmacol.com/PDF/jhp-11-286.pdf

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http://herbmedpharmacol.com/PDF/jhp-11-286.pdf

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