Low alanine aminotransferase activity gene variant in a Siberian Husky with copper-associated hepatopathy

Low alanine aminotransferase activity gene variant in a Siberian Husky with copper-associated hepatopathy

Abstract Background Alanine aminotransferase (ALT) is commonly used as a marker of hepatocellular injury. Increased serum ALT activity due to hepatocyte injury occurs in copper-associated hepatopathy (CuCH) and other necroinflammatory liver conditions. Blood ALT concentrations are frequently used to...

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Bibliographic Details
Main Authors: Christine Kim, John P. Loftus, Heather J. Huson
Format: Article
Language:English
Published: BMC 2023-08-01
Series:BMC Veterinary Research
Subjects:
Copper-associated hepatopathy
Alanine aminotransferase
Chronic hepatopathy
Canine
Genetics
Online Access:https://doi.org/10.1186/s12917-023-03681-6

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