A novel conceptual model of heart rate autonomic modulation based on a small-world modular structure of the sinoatrial node

The present view on heartbeat initiation is that a primary pacemaker cell or a group of cells in the sinoatrial node (SAN) center paces the rest of the SAN and the atria. However, recent high-resolution imaging studies show a more complex paradigm of SAN function that emerges from heterogeneous sign...

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Bibliographic Details
Main Authors: Alexander V. Maltsev, Michael D. Stern, Edward G. Lakatta, Victor A. Maltsev
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Physiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2023.1276023/full