Two cases of neglected leishmaniasis with marked facial disfigurement: A diagnostic conundrum
Key Clinical Message There is a need to pay more attention to cutaneous leishmaniasis in endemic regions which may mimic other dermatoses and treatment should be initiated with a strong clinical suspicion even without any histopathologic or PCR confirmation to avoid disfigurement or development of s...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2023-12-01
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| Series: | Clinical Case Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/ccr3.8268 |
| _version_ | 1797372167153778688 |
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| author | Zeinab Aryanian Kamran Balighi Fatameh Mohaghegh Ifa Etesami Zahra Razavi Parvaneh Hatami |
| author_facet | Zeinab Aryanian Kamran Balighi Fatameh Mohaghegh Ifa Etesami Zahra Razavi Parvaneh Hatami |
| author_sort | Zeinab Aryanian |
| collection | DOAJ |
| description | Key Clinical Message There is a need to pay more attention to cutaneous leishmaniasis in endemic regions which may mimic other dermatoses and treatment should be initiated with a strong clinical suspicion even without any histopathologic or PCR confirmation to avoid disfigurement or development of secondary malignancy. Abstract Leishmaniasis is a vector‐borne disease with a variety of Clinical manifestations. Cutaneous leishmaniasis (CL) is the most common form of disease and can mimic other dermatoses. We describe two unusual cases of chronic leishmaniasis that remained undiagnosed for many years and led to superimposition of squamous cell carcinoma (SCC) on lesions of one patient. These reports showed that the leishmaniasis should be borne in mind by clinicians when encountering any infiltrated lesion in patients from endemic regions and treatment should be initiated with a strong clinical suspicion even without any histopathologic or PCR confirmation to avoid disfigurement or development of secondary malignancy. |
| first_indexed | 2024-03-08T18:30:56Z |
| format | Article |
| id | doaj.art-a3058b67eee54db4b67077f5e087a208 |
| institution | Directory Open Access Journal |
| issn | 2050-0904 |
| language | English |
| last_indexed | 2024-03-08T18:30:56Z |
| publishDate | 2023-12-01 |
| publisher | Wiley |
| record_format | Article |
| series | Clinical Case Reports |
| spelling | doaj.art-a3058b67eee54db4b67077f5e087a2082023-12-30T04:35:08ZengWileyClinical Case Reports2050-09042023-12-011112n/an/a10.1002/ccr3.8268Two cases of neglected leishmaniasis with marked facial disfigurement: A diagnostic conundrumZeinab Aryanian0Kamran Balighi1Fatameh Mohaghegh2Ifa Etesami3Zahra Razavi4Parvaneh Hatami5Autoimmune Bullous Diseases Research Center Tehran University of Medical Sciences Tehran IranAutoimmune Bullous Diseases Research Center Tehran University of Medical Sciences Tehran IranDepartment of Dermatology, Skin Diseases and Leishmaniasis Research Center Isfahan University of Medical Sciences Isfahan IranAutoimmune Bullous Diseases Research Center Tehran University of Medical Sciences Tehran IranAutoimmune Bullous Diseases Research Center Tehran University of Medical Sciences Tehran IranAutoimmune Bullous Diseases Research Center Tehran University of Medical Sciences Tehran IranKey Clinical Message There is a need to pay more attention to cutaneous leishmaniasis in endemic regions which may mimic other dermatoses and treatment should be initiated with a strong clinical suspicion even without any histopathologic or PCR confirmation to avoid disfigurement or development of secondary malignancy. Abstract Leishmaniasis is a vector‐borne disease with a variety of Clinical manifestations. Cutaneous leishmaniasis (CL) is the most common form of disease and can mimic other dermatoses. We describe two unusual cases of chronic leishmaniasis that remained undiagnosed for many years and led to superimposition of squamous cell carcinoma (SCC) on lesions of one patient. These reports showed that the leishmaniasis should be borne in mind by clinicians when encountering any infiltrated lesion in patients from endemic regions and treatment should be initiated with a strong clinical suspicion even without any histopathologic or PCR confirmation to avoid disfigurement or development of secondary malignancy.https://doi.org/10.1002/ccr3.8268chronic lesionsgranulomatous dermatitisleishmaniasisneglected lesionSCC |
| spellingShingle | Zeinab Aryanian Kamran Balighi Fatameh Mohaghegh Ifa Etesami Zahra Razavi Parvaneh Hatami Two cases of neglected leishmaniasis with marked facial disfigurement: A diagnostic conundrum Clinical Case Reports chronic lesions granulomatous dermatitis leishmaniasis neglected lesion SCC |
| title | Two cases of neglected leishmaniasis with marked facial disfigurement: A diagnostic conundrum |
| title_full | Two cases of neglected leishmaniasis with marked facial disfigurement: A diagnostic conundrum |
| title_fullStr | Two cases of neglected leishmaniasis with marked facial disfigurement: A diagnostic conundrum |
| title_full_unstemmed | Two cases of neglected leishmaniasis with marked facial disfigurement: A diagnostic conundrum |
| title_short | Two cases of neglected leishmaniasis with marked facial disfigurement: A diagnostic conundrum |
| title_sort | two cases of neglected leishmaniasis with marked facial disfigurement a diagnostic conundrum |
| topic | chronic lesions granulomatous dermatitis leishmaniasis neglected lesion SCC |
| url | https://doi.org/10.1002/ccr3.8268 |
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