Deciphering genetic and nongenetic factors underlying tumour dormancy: insights from multiomics analysis of two syngeneic MRD models of melanoma and leukemia

Deciphering genetic and nongenetic factors underlying tumour dormancy: insights from multiomics analysis of two syngeneic MRD models of melanoma and leukemia

Abstract Background Tumour dormancy, a resistance mechanism employed by cancer cells, is a significant challenge in cancer treatment, contributing to minimal residual disease (MRD) and potential relapse. Despite its clinical importance, the mechanisms underlying tumour dormancy and MRD remain unclea...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Marie-Océane Laguillaumie, Sofia Titah, Aurélie Guillemette, Bernadette Neve, Frederic Leprêtre, Pascaline Ségard, Faruk Azam Shaik, Dominique Collard, Jean-Claude Gerbedoen, Léa Fléchon, Lama Hasan Bou Issa, Audrey Vincent, Martin Figeac, Shéhérazade Sebda, Céline Villenet, Jérôme Kluza, William Laine, Isabelle Fournier, Jean-Pascal Gimeno, Maxence Wisztorski, Salomon Manier, Mehmet Cagatay Tarhan, Bruno Quesnel, Thierry Idziorek, Yasmine Touil
التنسيق: مقال
اللغة:English
منشور في: BMC 2024-09-01
سلاسل:Biological Research
الموضوعات:
Tumour dormancy
Leukemia
Melanoma
Syngeneic model
Multiomics analysis
ChIP-seq
الوصول للمادة أونلاين:https://doi.org/10.1186/s40659-024-00540-y

الانترنت

https://doi.org/10.1186/s40659-024-00540-y

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