Avian pathogenic Escherichia coli T6SS effector protein Hcp2a causes mitochondrial dysfunction through interaction with LETM1 protein in DF-1 cells

Avian pathogenic Escherichia coli T6SS effector protein Hcp2a causes mitochondrial dysfunction through interaction with LETM1 protein in DF-1 cells

ABSTRACT: The type VI secretion system (T6SS) of avian pathogenic Escherichia coli (APEC) can affect the functions of eukaryotic cells by secreting or injecting effectors. Hemolysin co-regulatory protein (Hcp), one of the markers of the T6SS, is both a structural protein and an effector protein of t...

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Bibliographic Details
Main Authors: Liting Lu, Zhao Qi, Zhe Chen, Haiyang Wang, Xiyang Wei, Bingyu Zhao, Zhenyu Wang, Ying Shao, Jian Tu, Xiangjun Song
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:Poultry Science
Subjects:
avian pathogenic Escherichia coli
type VI secretion system
Hcp
mitochondrial dysfunction
DF-1 cell
Online Access:http://www.sciencedirect.com/science/article/pii/S0032579124000932

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