The New Kid on the Block: Online Adaptive Radiotherapy in the Treatment of Gynecologic Cancers

Online adaptive radiation is a new and exciting modality of treatment for gynecologic cancers. Traditional radiation treatments deliver the same radiation plan to cancers with large margins. Improvements in imaging, technology, and artificial intelligence have made it possible to account for changes...

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Main Authors: Allen Yen, Chenyang Shen, Kevin Albuquerque
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Current Oncology
Subjects:
Online Access:https://www.mdpi.com/1718-7729/30/1/66
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author Allen Yen
Chenyang Shen
Kevin Albuquerque
author_facet Allen Yen
Chenyang Shen
Kevin Albuquerque
author_sort Allen Yen
collection DOAJ
description Online adaptive radiation is a new and exciting modality of treatment for gynecologic cancers. Traditional radiation treatments deliver the same radiation plan to cancers with large margins. Improvements in imaging, technology, and artificial intelligence have made it possible to account for changes between treatments and improve the delivery of radiation. These advances can potentially lead to significant benefits in tumor coverage and normal tissue sparing. Gynecologic cancers can uniquely benefit from this technology due to the significant changes in bladder, bowel, and rectum between treatments as well as the changes in tumors commonly seen between treatments. Preliminary studies have shown that online adaptive radiation can maintain coverage of the tumor while sparing nearby organs. Given these potential benefits, numerous clinical trials are ongoing to investigate the clinical benefits of online adaptive radiotherapy. Despite the benefits, implementation of online adaptive radiotherapy requires significant clinical resources. Additionally, the timing and workflow for online adaptive radiotherapy is being optimized. In this review, we discuss the history and evolution of radiation techniques, the logistics and implementation of online adaptive radiation, and the potential benefits of online adaptive radiotherapy for gynecologic cancers.
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spelling doaj.art-a30c379c06114789b377afe484099d612023-11-30T21:49:47ZengMDPI AGCurrent Oncology1198-00521718-77292023-01-0130186587410.3390/curroncol30010066The New Kid on the Block: Online Adaptive Radiotherapy in the Treatment of Gynecologic CancersAllen Yen0Chenyang Shen1Kevin Albuquerque2Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USADepartment of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USADepartment of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USAOnline adaptive radiation is a new and exciting modality of treatment for gynecologic cancers. Traditional radiation treatments deliver the same radiation plan to cancers with large margins. Improvements in imaging, technology, and artificial intelligence have made it possible to account for changes between treatments and improve the delivery of radiation. These advances can potentially lead to significant benefits in tumor coverage and normal tissue sparing. Gynecologic cancers can uniquely benefit from this technology due to the significant changes in bladder, bowel, and rectum between treatments as well as the changes in tumors commonly seen between treatments. Preliminary studies have shown that online adaptive radiation can maintain coverage of the tumor while sparing nearby organs. Given these potential benefits, numerous clinical trials are ongoing to investigate the clinical benefits of online adaptive radiotherapy. Despite the benefits, implementation of online adaptive radiotherapy requires significant clinical resources. Additionally, the timing and workflow for online adaptive radiotherapy is being optimized. In this review, we discuss the history and evolution of radiation techniques, the logistics and implementation of online adaptive radiation, and the potential benefits of online adaptive radiotherapy for gynecologic cancers.https://www.mdpi.com/1718-7729/30/1/66gynecologic canceronline adaptive radiotherapyradiation oncology
spellingShingle Allen Yen
Chenyang Shen
Kevin Albuquerque
The New Kid on the Block: Online Adaptive Radiotherapy in the Treatment of Gynecologic Cancers
Current Oncology
gynecologic cancer
online adaptive radiotherapy
radiation oncology
title The New Kid on the Block: Online Adaptive Radiotherapy in the Treatment of Gynecologic Cancers
title_full The New Kid on the Block: Online Adaptive Radiotherapy in the Treatment of Gynecologic Cancers
title_fullStr The New Kid on the Block: Online Adaptive Radiotherapy in the Treatment of Gynecologic Cancers
title_full_unstemmed The New Kid on the Block: Online Adaptive Radiotherapy in the Treatment of Gynecologic Cancers
title_short The New Kid on the Block: Online Adaptive Radiotherapy in the Treatment of Gynecologic Cancers
title_sort new kid on the block online adaptive radiotherapy in the treatment of gynecologic cancers
topic gynecologic cancer
online adaptive radiotherapy
radiation oncology
url https://www.mdpi.com/1718-7729/30/1/66
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