A proportion of CD4+ T cells from patients with chronic Chagas disease undergo a dysfunctional process, which is partially reversed by benznidazole treatment.

<h4>Background</h4>Signs of senescence and the late stages of differentiation associated with the more severe forms of Chagas disease have been described in the Trypanosoma cruzi antigen-specific CD4+ T-cell population. However, the mechanisms involved in these functions are not fully kn...

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Bibliographic Details
Main Authors: Elena Pérez-Antón, Adriana Egui, M Carmen Thomas, Bartolomé Carrilero, Marina Simón, Miguel Ángel López-Ruz, Manuel Segovia, Manuel Carlos López
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-02-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0009059

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