Remnant neuromuscular junctions in denervated muscles contribute to functional recovery in delayed peripheral nerve repair

Remnant neuromuscular junctions in denervated muscles contribute to functional recovery in delayed peripheral nerve repair

Schwann cell proliferation in peripheral nerve injury (PNI) enhances axonal regeneration compared to central nerve injury. However, even in PNI, long-term nerve damage without repair induces degeneration of neuromuscular junctions (NMJs), and muscle atrophy results in irreversible dysfunction. The p...

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Bibliographic Details
Main Authors: Leyang Li, Hiroyuki Yokoyama, Hidetoshi Kaburagi, Takashi Hirai, Kunikazu Tsuji, Mitsuhiro Enomoto, Yoshiaki Wakabayashi, Atsushi Okawa
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2020-01-01
Series:Neural Regeneration Research
Subjects:
axon; nerve allograft; nerve regeneration; neurodegeneration; neuromuscular junction; peripheral nerve injury; schwann cell; skeletal muscle
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2020;volume=15;issue=4;spage=731;epage=738;aulast=Li

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