Photocytotoxicity studies of polyamidoamine (PAMAM) dendrimer and its glucoheptoamidated derivative as delivery drug systems in local PUVA photochemotherapy

Photocytotoxicity studies of polyamidoamine (PAMAM) dendrimer and its glucoheptoamidated derivative as delivery drug systems in local PUVA photochemotherapy

8-methoxypsoralen (8-MOP) given topically in local PUVA photochemotherapy poorly penetrates through the skin to its deeper layers which restricts its effectiveness. Poly(amidoamine) (PAMAM) dendrimers enhanced 8-MOP permeation through the skin. The aim of this study was to investigate photocytotoxi...

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Bibliographic Details
Main Authors: Katarzyna Borowska, Sebastian Radej, Ryszard Galus, Dariusz Śladowski, Wiktor Paskal, Dawid Mehlich, Stanisław Wołowiec
Format: Article
Language:English
Published: Our Dermatology Online 2017-10-01
Series:Nasza Dermatologia Online
Subjects:
PUVA
8-methoxypsoralen
Online Access:http://www.odermatol.com/online-section/case29/

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