Abdominal Mass Caused Failure to Thrive in a Young Boy: Mixed-Type Localized Retroperitoneal Castleman Disease
Castleman disease is a rare cause of retroperitoneal mass in children. Clinical presentation and laboratory findings are usually nonspecific. Imaging shows features of a hypervascular or soft tissue mass. We present a 12-year-old boy who complained of frequent colds, fatigue, and failure to gain wei...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Karger Publishers
2020-07-01
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| Series: | Case Reports in Oncology |
| Subjects: | |
| Online Access: | https://www.karger.com/Article/FullText/508531 |
| _version_ | 1819022084936826880 |
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| author | Bahar Ashjaei Afshar Ghamari Khameneh Gisoo Darban Hosseini Amirkhiz |
| author_facet | Bahar Ashjaei Afshar Ghamari Khameneh Gisoo Darban Hosseini Amirkhiz |
| author_sort | Bahar Ashjaei |
| collection | DOAJ |
| description | Castleman disease is a rare cause of retroperitoneal mass in children. Clinical presentation and laboratory findings are usually nonspecific. Imaging shows features of a hypervascular or soft tissue mass. We present a 12-year-old boy who complained of frequent colds, fatigue, and failure to gain weight for the past 4 years who was referred to our hospital. Anemia and hypergammaglobulinemia were revealed in laboratory tests. Imaging showed a well-delineated retroperitoneal soft tissue mass with intense homogenous enhancement at the midline below the aortic bifurcation. The histopathological features were consistent with mixed type unicentric Castleman disease. Surgical removal was curative. Our patient’s hematological abnormalities resolved, and he gained 10 kg in the next 4 weeks after the operation and reached the 25–50th percentile for his age. |
| first_indexed | 2024-12-21T04:17:23Z |
| format | Article |
| id | doaj.art-a313e16513da4a3e87eecff4aab64c19 |
| institution | Directory Open Access Journal |
| issn | 1662-6575 |
| language | English |
| last_indexed | 2024-12-21T04:17:23Z |
| publishDate | 2020-07-01 |
| publisher | Karger Publishers |
| record_format | Article |
| series | Case Reports in Oncology |
| spelling | doaj.art-a313e16513da4a3e87eecff4aab64c192022-12-21T19:16:16ZengKarger PublishersCase Reports in Oncology1662-65752020-07-0113285385610.1159/000508531508531Abdominal Mass Caused Failure to Thrive in a Young Boy: Mixed-Type Localized Retroperitoneal Castleman DiseaseBahar AshjaeiAfshar Ghamari KhamenehGisoo Darban Hosseini AmirkhizCastleman disease is a rare cause of retroperitoneal mass in children. Clinical presentation and laboratory findings are usually nonspecific. Imaging shows features of a hypervascular or soft tissue mass. We present a 12-year-old boy who complained of frequent colds, fatigue, and failure to gain weight for the past 4 years who was referred to our hospital. Anemia and hypergammaglobulinemia were revealed in laboratory tests. Imaging showed a well-delineated retroperitoneal soft tissue mass with intense homogenous enhancement at the midline below the aortic bifurcation. The histopathological features were consistent with mixed type unicentric Castleman disease. Surgical removal was curative. Our patient’s hematological abnormalities resolved, and he gained 10 kg in the next 4 weeks after the operation and reached the 25–50th percentile for his age.https://www.karger.com/Article/FullText/508531castleman diseaseretroperitoneumpediatricfailure to thriveanemia |
| spellingShingle | Bahar Ashjaei Afshar Ghamari Khameneh Gisoo Darban Hosseini Amirkhiz Abdominal Mass Caused Failure to Thrive in a Young Boy: Mixed-Type Localized Retroperitoneal Castleman Disease Case Reports in Oncology castleman disease retroperitoneum pediatric failure to thrive anemia |
| title | Abdominal Mass Caused Failure to Thrive in a Young Boy: Mixed-Type Localized Retroperitoneal Castleman Disease |
| title_full | Abdominal Mass Caused Failure to Thrive in a Young Boy: Mixed-Type Localized Retroperitoneal Castleman Disease |
| title_fullStr | Abdominal Mass Caused Failure to Thrive in a Young Boy: Mixed-Type Localized Retroperitoneal Castleman Disease |
| title_full_unstemmed | Abdominal Mass Caused Failure to Thrive in a Young Boy: Mixed-Type Localized Retroperitoneal Castleman Disease |
| title_short | Abdominal Mass Caused Failure to Thrive in a Young Boy: Mixed-Type Localized Retroperitoneal Castleman Disease |
| title_sort | abdominal mass caused failure to thrive in a young boy mixed type localized retroperitoneal castleman disease |
| topic | castleman disease retroperitoneum pediatric failure to thrive anemia |
| url | https://www.karger.com/Article/FullText/508531 |
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