Pricing and cost-saving potential for deep-learning computer-aided lung nodule detection software in CT lung cancer screening

Abstract Objective An increasing number of commercial deep learning computer-aided detection (DL-CAD) systems are available but their cost-saving potential is largely unknown. This study aimed to gain insight into appropriate pricing for DL-CAD in different reading modes to be cost-saving and to det...

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Main Authors: Yihui Du, Marcel J. W. Greuter, Mathias W. Prokop, Geertruida H. de Bock
Format: Article
Language:English
Published: SpringerOpen 2023-11-01
Series:Insights into Imaging
Subjects:
Online Access:https://doi.org/10.1186/s13244-023-01561-z
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author Yihui Du
Marcel J. W. Greuter
Mathias W. Prokop
Geertruida H. de Bock
author_facet Yihui Du
Marcel J. W. Greuter
Mathias W. Prokop
Geertruida H. de Bock
author_sort Yihui Du
collection DOAJ
description Abstract Objective An increasing number of commercial deep learning computer-aided detection (DL-CAD) systems are available but their cost-saving potential is largely unknown. This study aimed to gain insight into appropriate pricing for DL-CAD in different reading modes to be cost-saving and to determine the potentially most cost-effective reading mode for lung cancer screening. Methods In three representative settings, DL-CAD was evaluated as a concurrent, pre-screening, and second reader. Scoping review was performed to estimate radiologist reading time with and without DL-CAD. Hourly cost of radiologist time was collected for the USA (€196), UK (€127), and Poland (€45), and monetary equivalence of saved time was calculated. The minimum number of screening CTs to reach break-even was calculated for one-time investment of €51,616 for DL-CAD. Results Mean reading time was 162 (95% CI: 111–212) seconds per case without DL-CAD, which decreased by 77 (95% CI: 47–107) and 104 (95% CI: 71–136) seconds for DL-CAD as concurrent and pre-screening reader, respectively, and increased by 33–41 s for DL-CAD as second reader. This translates into €1.0–4.3 per-case cost for concurrent reading and €0.8–5.7 for pre-screening reading in the USA, UK, and Poland. To achieve break-even with a one-time investment, the minimum number of CT scans was 12,300–53,600 for concurrent reader, and 9400–65,000 for pre-screening reader in the three countries. Conclusions Given current pricing, DL-CAD must be priced substantially below €6 in a pay-per-case setting or used in a high-workload environment to reach break-even in lung cancer screening. DL-CAD as pre-screening reader shows the largest potential to be cost-saving. Critical relevance statement Deep-learning computer-aided lung nodule detection (DL-CAD) software must be priced substantially below 6 euro in a pay-per-case setting or must be used in high-workload environments with one-time investment in order to achieve break-even. DL-CAD as a pre-screening reader has the greatest cost savings potential. Key points • DL-CAD must be substantially below €6 in a pay-per-case setting to reach break-even. • DL-CAD must be used in a high-workload screening environment to achieve break-even. • DL-CAD as a pre-screening reader shows the largest potential to be cost-saving. Graphical Abstract
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spelling doaj.art-a3146910efb042dd947bc6a116e6f81d2023-12-03T12:25:11ZengSpringerOpenInsights into Imaging1869-41012023-11-011411710.1186/s13244-023-01561-zPricing and cost-saving potential for deep-learning computer-aided lung nodule detection software in CT lung cancer screeningYihui Du0Marcel J. W. Greuter1Mathias W. Prokop2Geertruida H. de Bock3Department of Epidemiology and Health Statistics, School of Public Health, Hangzhou Normal UniversityDepartment of Radiology, University Medical Center Groningen, University of GroningenDepartment of Radiology, University Medical Center Groningen, University of GroningenDepartment of Epidemiology, University Medical Center Groningen, University of GroningenAbstract Objective An increasing number of commercial deep learning computer-aided detection (DL-CAD) systems are available but their cost-saving potential is largely unknown. This study aimed to gain insight into appropriate pricing for DL-CAD in different reading modes to be cost-saving and to determine the potentially most cost-effective reading mode for lung cancer screening. Methods In three representative settings, DL-CAD was evaluated as a concurrent, pre-screening, and second reader. Scoping review was performed to estimate radiologist reading time with and without DL-CAD. Hourly cost of radiologist time was collected for the USA (€196), UK (€127), and Poland (€45), and monetary equivalence of saved time was calculated. The minimum number of screening CTs to reach break-even was calculated for one-time investment of €51,616 for DL-CAD. Results Mean reading time was 162 (95% CI: 111–212) seconds per case without DL-CAD, which decreased by 77 (95% CI: 47–107) and 104 (95% CI: 71–136) seconds for DL-CAD as concurrent and pre-screening reader, respectively, and increased by 33–41 s for DL-CAD as second reader. This translates into €1.0–4.3 per-case cost for concurrent reading and €0.8–5.7 for pre-screening reading in the USA, UK, and Poland. To achieve break-even with a one-time investment, the minimum number of CT scans was 12,300–53,600 for concurrent reader, and 9400–65,000 for pre-screening reader in the three countries. Conclusions Given current pricing, DL-CAD must be priced substantially below €6 in a pay-per-case setting or used in a high-workload environment to reach break-even in lung cancer screening. DL-CAD as pre-screening reader shows the largest potential to be cost-saving. Critical relevance statement Deep-learning computer-aided lung nodule detection (DL-CAD) software must be priced substantially below 6 euro in a pay-per-case setting or must be used in high-workload environments with one-time investment in order to achieve break-even. DL-CAD as a pre-screening reader has the greatest cost savings potential. Key points • DL-CAD must be substantially below €6 in a pay-per-case setting to reach break-even. • DL-CAD must be used in a high-workload screening environment to achieve break-even. • DL-CAD as a pre-screening reader shows the largest potential to be cost-saving. Graphical Abstracthttps://doi.org/10.1186/s13244-023-01561-zDeep learningComputed aid detectionPricingLung noduleLung cancer screening
spellingShingle Yihui Du
Marcel J. W. Greuter
Mathias W. Prokop
Geertruida H. de Bock
Pricing and cost-saving potential for deep-learning computer-aided lung nodule detection software in CT lung cancer screening
Insights into Imaging
Deep learning
Computed aid detection
Pricing
Lung nodule
Lung cancer screening
title Pricing and cost-saving potential for deep-learning computer-aided lung nodule detection software in CT lung cancer screening
title_full Pricing and cost-saving potential for deep-learning computer-aided lung nodule detection software in CT lung cancer screening
title_fullStr Pricing and cost-saving potential for deep-learning computer-aided lung nodule detection software in CT lung cancer screening
title_full_unstemmed Pricing and cost-saving potential for deep-learning computer-aided lung nodule detection software in CT lung cancer screening
title_short Pricing and cost-saving potential for deep-learning computer-aided lung nodule detection software in CT lung cancer screening
title_sort pricing and cost saving potential for deep learning computer aided lung nodule detection software in ct lung cancer screening
topic Deep learning
Computed aid detection
Pricing
Lung nodule
Lung cancer screening
url https://doi.org/10.1186/s13244-023-01561-z
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