Construction of an alternative NADPH regeneration pathway improves ethanol production in Saccharomyces cerevisiae with xylose metabolic pathway

Construction of an alternative NADPH regeneration pathway improves ethanol production in Saccharomyces cerevisiae with xylose metabolic pathway

Full conversion of glucose and xylose from lignocellulosic hydrolysates is required for obtaining a high ethanol yield. However, glucose and xylose share flux in the pentose phosphate pathway (PPP) and glycolysis pathway (EMP), with glucose having a competitive advantage in the shared metabolic path...

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Bibliographic Details
Main Authors: Yali Qiu, Wei Liu, Meiling Wu, Haodong Bao, Xinhua Sun, Qin Dou, Hongying Jia, Weifeng Liu, Yu Shen
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2024-06-01
Series:Synthetic and Systems Biotechnology
Subjects:
Saccharomyces cerevisiae
Xylose
Ethanol
NADPH
Glyceraldehyde-3-phosphate dehydrogenase
Online Access:http://www.sciencedirect.com/science/article/pii/S2405805X24000292

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