Glutathione S-Transferase Gene Polymorphisms as Predictors of Methotrexate Efficacy in Juvenile Idiopathic Arthritis

Glutathione S-Transferase Gene Polymorphisms as Predictors of Methotrexate Efficacy in Juvenile Idiopathic Arthritis

Because of the unpredictable efficacy of methotrexate (MTX) in the treatment of juvenile idiopathic arthritis (JIA), the possibility of a favourable outcome is reduced in more than 30% of patients. To investigate the possible influence of glutathione S-transferase M1 (GSTM1) and T1 (GSTT1) gene dele...

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Bibliographic Details
Main Authors: Sanda Huljev Frkovic, Marija Jelusic, Kristina Crkvenac Gornik, Dunja Rogic, Marijan Frkovic
Format: Article
Language:English
Published: MDPI AG 2024-07-01
Series:Biomedicines
Subjects:
juvenile idiopathic arthritis
biomarker
glutathione S-transferase
methotrexate
efficacy
Online Access:https://www.mdpi.com/2227-9059/12/8/1642

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https://www.mdpi.com/2227-9059/12/8/1642

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