Glutathione S-Transferase Gene Polymorphisms as Predictors of Methotrexate Efficacy in Juvenile Idiopathic Arthritis

Glutathione S-Transferase Gene Polymorphisms as Predictors of Methotrexate Efficacy in Juvenile Idiopathic Arthritis

Because of the unpredictable efficacy of methotrexate (MTX) in the treatment of juvenile idiopathic arthritis (JIA), the possibility of a favourable outcome is reduced in more than 30% of patients. To investigate the possible influence of glutathione S-transferase M1 (GSTM1) and T1 (GSTT1) gene dele...

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Bibliografski detalji
Glavni autori: Sanda Huljev Frkovic, Marija Jelusic, Kristina Crkvenac Gornik, Dunja Rogic, Marijan Frkovic
Format: Članak
Jezik:English
Izdano: MDPI AG 2024-07-01
Serija:Biomedicines
Teme:
juvenile idiopathic arthritis
biomarker
glutathione S-transferase
methotrexate
efficacy
Online pristup:https://www.mdpi.com/2227-9059/12/8/1642

Internet

https://www.mdpi.com/2227-9059/12/8/1642

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