Box-Behnken Assisted Validation and Optimization of an RP-HPLC Method for Simultaneous Determination of Domperidone and Lansoprazole

Box-Behnken Assisted Validation and Optimization of an RP-HPLC Method for Simultaneous Determination of Domperidone and Lansoprazole

A highly specific, accurate, and simple RP-HPLC technique was developed for the real-time quantification of domperidone (DOMP) and lansoprazole (LANS) in commercial formulations. Chromatographic studies were performed using a Luna C8(2), 5 μm, 100Å, column (250 × 4.6 mm, Phenomenex) with a mobile ph...

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Bibliographic Details
Main Authors: Mohd Afzal, Mohd. Muddassir, Abdullah Alarifi, Mohammed Tahir Ansari
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Separations
Subjects:
lansoprazole
domperidone
method validation
Box–Behnken
chromatography
Online Access:https://www.mdpi.com/2297-8739/8/1/5

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