A comparison of RNA extraction and sequencing protocols for detection of small RNAs in plasma

A comparison of RNA extraction and sequencing protocols for detection of small RNAs in plasma

Abstract Background Circulating microRNAs (miRNAs) are attractive non-invasive biomarkers for a variety of conditions due to their stability and altered pathophysiological expression levels. Reliable detection of global expression profiles is required to maximise miRNA biomarker discovery. Although...

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Bibliographic Details
Main Authors: Ryan K.Y. Wong, Meabh MacMahon, Jayne V. Woodside, David A. Simpson
Format: Article
Language:English
Published: BMC 2019-06-01
Series:BMC Genomics
Subjects:
microRNA
miRNA
Small RNA-Seq
Circulating biomarker
Next generation sequencing
NGS
Online Access:http://link.springer.com/article/10.1186/s12864-019-5826-7

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