Ocular Surface Squamous Neoplasia: Monotherapy with Mitomycin C

ABSTRACT Ocular Surface Squamous Neoplasia (OSSN) is a neoplasm of ocular surface present in the interpalpebral area having feeder vessel. It is more common in middle age group and present as a mass lesion or chronic ocular irritation. Treatment is chemo reduction, surgical excision, cryotherapy an...

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Main Author: Manu Sharma
Format: Article
Language:English
Published: JCDR Research and Publications Private Limited 2020-06-01
Series:Journal of Clinical and Diagnostic Research
Subjects:
Online Access:https://jcdr.net/articles/PDF/13776/43814_CE[Ra1]_F(SHU)_PF1(AJ_KM)_GC(AJ_KM)_PN(SL).pdf
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author Manu Sharma
author_facet Manu Sharma
author_sort Manu Sharma
collection DOAJ
description ABSTRACT Ocular Surface Squamous Neoplasia (OSSN) is a neoplasm of ocular surface present in the interpalpebral area having feeder vessel. It is more common in middle age group and present as a mass lesion or chronic ocular irritation. Treatment is chemo reduction, surgical excision, cryotherapy and excision with adjuvant chemotherapy. There is high rate of recurrence in OSSN. Here, a case of 79-year-old female patient with painless mass over conjunctiva and cornea was presented. The mass was whitish, shiny and placoid extending from 9 o’clock to 5 o’clock position covering half of the corneal surface with feeder vessel. Gelatinous or leucoplakic OSSN was managed with chemoreduction and monotherapy with mitomycin C. No recurrence was reported during more than 2 years follow-up at the peripheral health institution.
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spelling doaj.art-a323012af18a4178896f2b4df504d0402022-12-22T00:29:59ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2020-06-01146ND01ND0210.7860/JCDR/2020/43814.13776Ocular Surface Squamous Neoplasia: Monotherapy with Mitomycin CManu Sharma0Medical Officer, Department of Health and Family Welfare, Civil Hospital, Kangra, Himachal Pradesh, India.ABSTRACT Ocular Surface Squamous Neoplasia (OSSN) is a neoplasm of ocular surface present in the interpalpebral area having feeder vessel. It is more common in middle age group and present as a mass lesion or chronic ocular irritation. Treatment is chemo reduction, surgical excision, cryotherapy and excision with adjuvant chemotherapy. There is high rate of recurrence in OSSN. Here, a case of 79-year-old female patient with painless mass over conjunctiva and cornea was presented. The mass was whitish, shiny and placoid extending from 9 o’clock to 5 o’clock position covering half of the corneal surface with feeder vessel. Gelatinous or leucoplakic OSSN was managed with chemoreduction and monotherapy with mitomycin C. No recurrence was reported during more than 2 years follow-up at the peripheral health institution.https://jcdr.net/articles/PDF/13776/43814_CE[Ra1]_F(SHU)_PF1(AJ_KM)_GC(AJ_KM)_PN(SL).pdfchemoreductioncryotherapyocular squamous neoplasia
spellingShingle Manu Sharma
Ocular Surface Squamous Neoplasia: Monotherapy with Mitomycin C
Journal of Clinical and Diagnostic Research
chemoreduction
cryotherapy
ocular squamous neoplasia
title Ocular Surface Squamous Neoplasia: Monotherapy with Mitomycin C
title_full Ocular Surface Squamous Neoplasia: Monotherapy with Mitomycin C
title_fullStr Ocular Surface Squamous Neoplasia: Monotherapy with Mitomycin C
title_full_unstemmed Ocular Surface Squamous Neoplasia: Monotherapy with Mitomycin C
title_short Ocular Surface Squamous Neoplasia: Monotherapy with Mitomycin C
title_sort ocular surface squamous neoplasia monotherapy with mitomycin c
topic chemoreduction
cryotherapy
ocular squamous neoplasia
url https://jcdr.net/articles/PDF/13776/43814_CE[Ra1]_F(SHU)_PF1(AJ_KM)_GC(AJ_KM)_PN(SL).pdf
work_keys_str_mv AT manusharma ocularsurfacesquamousneoplasiamonotherapywithmitomycinc