Recent advances in understanding and managing retinal vein occlusions [version 1; referees: 3 approved]

Retinal vein occlusions are the second most common form of retinal vascular disease. Previously, laser treatment for branch retinal vein occlusion and intravitreal triamcinolone acetonide for central retinal vein occlusion were the standard of care. Recent studies have demonstrated that anti-vascula...

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Main Authors: Daniel D. Esmaili, David S. Boyer
Format: Article
Language:English
Published: F1000 Research Ltd 2018-04-01
Series:F1000Research
Online Access:https://f1000research.com/articles/7-467/v1
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author Daniel D. Esmaili
David S. Boyer
author_facet Daniel D. Esmaili
David S. Boyer
author_sort Daniel D. Esmaili
collection DOAJ
description Retinal vein occlusions are the second most common form of retinal vascular disease. Previously, laser treatment for branch retinal vein occlusion and intravitreal triamcinolone acetonide for central retinal vein occlusion were the standard of care. Recent studies have demonstrated that anti-vascular endothelial growth factor (anti-VEGF) agents have a superior safety and efficacy profile for the treatment of both branch and central retinal vein occlusions. The use of wide-field fluorescein angiography has also allowed better visualization of the retinal periphery. Despite the better documentation of retinal non-perfusion, laser photocoagulation to the areas of non-perfusion does not seem to result in a reduction of macular edema or reduction in treatment burden and has been relegated to patients who develop rubeosis or neovascularization of the retina. More recently, several studies have demonstrated the use of a long-acting dexamethasone implant administered intravitreally or triamcinolone administered in the suprachoroidal space as a viable approach to treat retinal vein occlusion.
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spelling doaj.art-a323b55365ff46308c4ac28aa868dd632022-12-22T00:04:57ZengF1000 Research LtdF1000Research2046-14022018-04-01710.12688/f1000research.12886.113968Recent advances in understanding and managing retinal vein occlusions [version 1; referees: 3 approved]Daniel D. Esmaili0David S. Boyer1Retina-Vitreous Associates Medical Group, 001 Wilshire Boulevard, Suite 301, Beverly Hills, CA 90211, USARetina-Vitreous Associates Medical Group, 001 Wilshire Boulevard, Suite 301, Beverly Hills, CA 90211, USARetinal vein occlusions are the second most common form of retinal vascular disease. Previously, laser treatment for branch retinal vein occlusion and intravitreal triamcinolone acetonide for central retinal vein occlusion were the standard of care. Recent studies have demonstrated that anti-vascular endothelial growth factor (anti-VEGF) agents have a superior safety and efficacy profile for the treatment of both branch and central retinal vein occlusions. The use of wide-field fluorescein angiography has also allowed better visualization of the retinal periphery. Despite the better documentation of retinal non-perfusion, laser photocoagulation to the areas of non-perfusion does not seem to result in a reduction of macular edema or reduction in treatment burden and has been relegated to patients who develop rubeosis or neovascularization of the retina. More recently, several studies have demonstrated the use of a long-acting dexamethasone implant administered intravitreally or triamcinolone administered in the suprachoroidal space as a viable approach to treat retinal vein occlusion.https://f1000research.com/articles/7-467/v1
spellingShingle Daniel D. Esmaili
David S. Boyer
Recent advances in understanding and managing retinal vein occlusions [version 1; referees: 3 approved]
F1000Research
title Recent advances in understanding and managing retinal vein occlusions [version 1; referees: 3 approved]
title_full Recent advances in understanding and managing retinal vein occlusions [version 1; referees: 3 approved]
title_fullStr Recent advances in understanding and managing retinal vein occlusions [version 1; referees: 3 approved]
title_full_unstemmed Recent advances in understanding and managing retinal vein occlusions [version 1; referees: 3 approved]
title_short Recent advances in understanding and managing retinal vein occlusions [version 1; referees: 3 approved]
title_sort recent advances in understanding and managing retinal vein occlusions version 1 referees 3 approved
url https://f1000research.com/articles/7-467/v1
work_keys_str_mv AT danieldesmaili recentadvancesinunderstandingandmanagingretinalveinocclusionsversion1referees3approved
AT davidsboyer recentadvancesinunderstandingandmanagingretinalveinocclusionsversion1referees3approved