IGF2BP2 Regulates MALAT1 by Serving as an N6-Methyladenosine Reader to Promote NSCLC Proliferation

Insulin-like growth factor 2 (IGF2) mRNA-binding protein 2 (IGF2BP2) is an important posttranscriptional regulatory for stability and m6A modification. Here, we investigated the role of IGF2BP2 in non–small-cell lung cancer (NSCLC) proliferation. TCGA database was used to predict the expression and...

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Hlavní autoři: Le Han, Guangyan Lei, Zhenghong Chen, Yili Zhang, Chen Huang, Wenjuan Chen
Médium: Článek
Jazyk:English
Vydáno: Frontiers Media S.A. 2022-01-01
Edice:Frontiers in Molecular Biosciences
Témata:
On-line přístup:https://www.frontiersin.org/articles/10.3389/fmolb.2021.780089/full