IGF2BP2 Regulates MALAT1 by Serving as an N6-Methyladenosine Reader to Promote NSCLC Proliferation

IGF2BP2 Regulates MALAT1 by Serving as an N6-Methyladenosine Reader to Promote NSCLC Proliferation

Insulin-like growth factor 2 (IGF2) mRNA-binding protein 2 (IGF2BP2) is an important posttranscriptional regulatory for stability and m6A modification. Here, we investigated the role of IGF2BP2 in non–small-cell lung cancer (NSCLC) proliferation. TCGA database was used to predict the expression and...

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Bibliographic Details
Main Authors: Le Han, Guangyan Lei, Zhenghong Chen, Yili Zhang, Chen Huang, Wenjuan Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Molecular Biosciences
Subjects:
NSCLC
IGF2BP2
M6A
MALAT1
ATG12
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2021.780089/full

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