Investigation of a monophasic Salmonella Typhimurium outbreak linked to chocolate products as part of wider international outbreak: A matched case–control study, Ireland, 2022
Abstract Background In March 2022, an outbreak investigation was initiated in Ireland after identifying a cluster of monophasic Salmonella Typhimurium cases, affecting primarily small children. Microbiological investigations revealed that the cluster was part of a wider international outbreak. Metho...
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| Định dạng: | Bài viết |
| Ngôn ngữ: | English |
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Wiley
2023-12-01
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| Loạt: | Public Health Challenges |
| Những chủ đề: | |
| Truy cập trực tuyến: | https://doi.org/10.1002/puh2.116 |
| _version_ | 1827395494537592832 |
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| author | Charlotte Salgaard Nielsen Patricia Garvey Martin Cormican Niall DeLappe Mary Lenahan Orla Moore Kay Casey Suzanne Cotter Sarah Gee Benjamin Aniugbo Gerard Meagher Elaine Brabazon Keith Ian Quintyne Anthony Breslin RoseMary McBride Eimear Burke Margaret White Marie Casey Leah Evans Catherine Conlon Annette Dillon Regina Kiernan Donna Kilmartin Cale Lawlor Ruth McDermott Paul McKeown Outbreak Control Team |
| author_facet | Charlotte Salgaard Nielsen Patricia Garvey Martin Cormican Niall DeLappe Mary Lenahan Orla Moore Kay Casey Suzanne Cotter Sarah Gee Benjamin Aniugbo Gerard Meagher Elaine Brabazon Keith Ian Quintyne Anthony Breslin RoseMary McBride Eimear Burke Margaret White Marie Casey Leah Evans Catherine Conlon Annette Dillon Regina Kiernan Donna Kilmartin Cale Lawlor Ruth McDermott Paul McKeown Outbreak Control Team |
| author_sort | Charlotte Salgaard Nielsen |
| collection | DOAJ |
| description | Abstract Background In March 2022, an outbreak investigation was initiated in Ireland after identifying a cluster of monophasic Salmonella Typhimurium cases, affecting primarily small children. Microbiological investigations revealed that the cluster was part of a wider international outbreak. Methods A total of 18 Irish outbreak cases were identified. We undertook a matched case–control study using the case–case method to determine if exposure to the implicated products was associated with illness. Results In univariable analysis, the highest odds of disease due to monophasic S. Typhimurium versus other gastrointestinal disease were obtained for a chocolate Product A of Brand A [matched odds ratio (mOR) = 7.77, 95% confidence intervals (CI): 0.89–67.20]. When grouping the implicated products in a composite variable, the odds of disease due to monophasic S. Typhimurium versus other gastrointestinal disease were 10.5 times higher with a consumption of at least one of the implicated products [mOR = 10.50, 95% CI: 1.24–88.60, p = 0.031]. Conclusion This analytical study supported the internationally generated hypothesis which led to the implementation of control measures. Owing to the high levels of chocolate purchasing with Easter approaching, early outbreak identification and involvement in the internationally coordinated investigation was essential to an efficient response and to minimise the risk of further harm to a particularly vulnerable population group. |
| first_indexed | 2024-03-08T18:33:55Z |
| format | Article |
| id | doaj.art-a3252fd0c1cb4d04bbfbdf5b8c0fb658 |
| institution | Directory Open Access Journal |
| issn | 2769-2450 |
| language | English |
| last_indexed | 2024-03-08T18:33:55Z |
| publishDate | 2023-12-01 |
| publisher | Wiley |
| record_format | Article |
| series | Public Health Challenges |
| spelling | doaj.art-a3252fd0c1cb4d04bbfbdf5b8c0fb6582023-12-29T16:48:31ZengWileyPublic Health Challenges2769-24502023-12-0124n/an/a10.1002/puh2.116Investigation of a monophasic Salmonella Typhimurium outbreak linked to chocolate products as part of wider international outbreak: A matched case–control study, Ireland, 2022Charlotte Salgaard Nielsen0Patricia Garvey1Martin Cormican2Niall DeLappe3Mary Lenahan4Orla Moore5Kay Casey6Suzanne Cotter7Sarah Gee8Benjamin Aniugbo9Gerard Meagher10Elaine Brabazon11Keith Ian Quintyne12Anthony Breslin13RoseMary McBride14Eimear Burke15Margaret White16Marie Casey17Leah Evans18Catherine Conlon19Annette Dillon20Regina Kiernan21Donna Kilmartin22Cale Lawlor23Ruth McDermott24Paul McKeown25Outbreak Control TeamHealth Service Executive (HSE)—Health Protection Surveillance Centre (HPSC) Dublin IrelandHealth Service Executive (HSE)—Health Protection Surveillance Centre (HPSC) Dublin IrelandNational Salmonella Shigella & Listeria Reference Laboratory Galway IrelandNational Salmonella Shigella & Listeria Reference Laboratory Galway IrelandFood Safety Authority of Ireland Dublin IrelandFood Safety Authority of Ireland Dublin IrelandEnvironmental Health Service Health Service Executive Dublin IrelandHealth Service Executive (HSE)—Health Protection Surveillance Centre (HPSC) Dublin IrelandHealth Service Executive (HSE)—Health Protection Surveillance Centre (HPSC) Dublin IrelandDepartment of Public Health Health Service Executive—Midlands Dublin IrelandDepartment of Public Health Health Service Executive—Midlands Dublin IrelandDepartment of Public Health Health Service Executive—North‐East Dublin IrelandDepartment of Public Health Health Service Executive—North‐East Dublin IrelandDepartment of Public Health Health Service Executive—North‐West Dublin IrelandDepartment of Public Health Health Service Executive—North‐West Dublin IrelandDepartment of Public Health Health Service Executive—South‐East Dublin IrelandDepartment of Public Health Health Service Executive—South‐East Dublin IrelandDepartment of Public Health Health Service Executive—Mid‐West Dublin IrelandDepartment of Public Health Health Service Executive—Mid‐West Dublin IrelandDepartment of Public Health Health Service Executive—South Dublin IrelandDepartment of Public Health Health Service Executive—South Dublin IrelandDepartment of Public Health Health Service Executive—West Dublin IrelandDepartment of Public Health Health Service Executive—West Dublin IrelandDepartment of Public Health Health Service Executive—East Dublin IrelandDepartment of Public Health Health Service Executive—East Dublin IrelandHealth Service Executive (HSE)—Health Protection Surveillance Centre (HPSC) Dublin IrelandAbstract Background In March 2022, an outbreak investigation was initiated in Ireland after identifying a cluster of monophasic Salmonella Typhimurium cases, affecting primarily small children. Microbiological investigations revealed that the cluster was part of a wider international outbreak. Methods A total of 18 Irish outbreak cases were identified. We undertook a matched case–control study using the case–case method to determine if exposure to the implicated products was associated with illness. Results In univariable analysis, the highest odds of disease due to monophasic S. Typhimurium versus other gastrointestinal disease were obtained for a chocolate Product A of Brand A [matched odds ratio (mOR) = 7.77, 95% confidence intervals (CI): 0.89–67.20]. When grouping the implicated products in a composite variable, the odds of disease due to monophasic S. Typhimurium versus other gastrointestinal disease were 10.5 times higher with a consumption of at least one of the implicated products [mOR = 10.50, 95% CI: 1.24–88.60, p = 0.031]. Conclusion This analytical study supported the internationally generated hypothesis which led to the implementation of control measures. Owing to the high levels of chocolate purchasing with Easter approaching, early outbreak identification and involvement in the internationally coordinated investigation was essential to an efficient response and to minimise the risk of further harm to a particularly vulnerable population group.https://doi.org/10.1002/puh2.116chocolatefoodborne diseaseoutbreakSalmonella Typhimurium |
| spellingShingle | Charlotte Salgaard Nielsen Patricia Garvey Martin Cormican Niall DeLappe Mary Lenahan Orla Moore Kay Casey Suzanne Cotter Sarah Gee Benjamin Aniugbo Gerard Meagher Elaine Brabazon Keith Ian Quintyne Anthony Breslin RoseMary McBride Eimear Burke Margaret White Marie Casey Leah Evans Catherine Conlon Annette Dillon Regina Kiernan Donna Kilmartin Cale Lawlor Ruth McDermott Paul McKeown Outbreak Control Team Investigation of a monophasic Salmonella Typhimurium outbreak linked to chocolate products as part of wider international outbreak: A matched case–control study, Ireland, 2022 Public Health Challenges chocolate foodborne disease outbreak Salmonella Typhimurium |
| title | Investigation of a monophasic Salmonella Typhimurium outbreak linked to chocolate products as part of wider international outbreak: A matched case–control study, Ireland, 2022 |
| title_full | Investigation of a monophasic Salmonella Typhimurium outbreak linked to chocolate products as part of wider international outbreak: A matched case–control study, Ireland, 2022 |
| title_fullStr | Investigation of a monophasic Salmonella Typhimurium outbreak linked to chocolate products as part of wider international outbreak: A matched case–control study, Ireland, 2022 |
| title_full_unstemmed | Investigation of a monophasic Salmonella Typhimurium outbreak linked to chocolate products as part of wider international outbreak: A matched case–control study, Ireland, 2022 |
| title_short | Investigation of a monophasic Salmonella Typhimurium outbreak linked to chocolate products as part of wider international outbreak: A matched case–control study, Ireland, 2022 |
| title_sort | investigation of a monophasic salmonella typhimurium outbreak linked to chocolate products as part of wider international outbreak a matched case control study ireland 2022 |
| topic | chocolate foodborne disease outbreak Salmonella Typhimurium |
| url | https://doi.org/10.1002/puh2.116 |
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