Neuroplastic effects of transcranial near-infrared stimulation (tNIRS) on the motor cortex
Near-infrared light stimulation of the brain has been claimed to improve deficits caused by traumatic brain injury and stroke. Here, we exploit the effect of transcranial near-infrared stimulation (tNIRS) as a tool to modulate cortical excitability in the healthy human brain. tNIRS was applied at a...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2015-06-01
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| Series: | Frontiers in Behavioral Neuroscience |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fnbeh.2015.00147/full |
| _version_ | 1811215785824092160 |
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| author | Leila eChaieb Andrea eAntal Florentin eMasurat Walter ePaulus |
| author_facet | Leila eChaieb Andrea eAntal Florentin eMasurat Walter ePaulus |
| author_sort | Leila eChaieb |
| collection | DOAJ |
| description | Near-infrared light stimulation of the brain has been claimed to improve deficits caused by traumatic brain injury and stroke. Here, we exploit the effect of transcranial near-infrared stimulation (tNIRS) as a tool to modulate cortical excitability in the healthy human brain. tNIRS was applied at a wavelength of 810 nm for 10 minutes over the hand area of the primary motor cortex (M1). Both single-pulse and paired-pulse measures of transcranial magnetic stimulation (TMS) were used to assess levels of cortical excitability in the corticospinal pathway and intracortical circuits. The serial reaction time task (SRTT) was used to investigate the possible effect of tNIRS on implicit learning.By evaluating the mean amplitude of single-pulse TMS elicited motor-evoked-potentials (MEPs) a significant decrease of the amplitude was observed up to 30 minutes post-stimulation, compared to baseline. Furthermore, the short interval cortical inhibition (SICI) was increased and facilitation (ICF) decreased significantly after tNIRS. The results from the SRTT experiment show that there was no net effect of stimulation on the performance of the participants. Results of a study questionnaire demonstrated that tNIRS did not induce serious side effects apart from light headache and fatigue. Nevertheless, 66% were able to detect the difference between active and sham stimulation conditions.In this study we provide further evidence that tNIRS is suitable as a tool for influencing cortical excitability and activity in the healthy human brain. |
| first_indexed | 2024-04-12T06:29:30Z |
| format | Article |
| id | doaj.art-a32780a2411d4c15acc300d6d5ff9259 |
| institution | Directory Open Access Journal |
| issn | 1662-5153 |
| language | English |
| last_indexed | 2024-04-12T06:29:30Z |
| publishDate | 2015-06-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Behavioral Neuroscience |
| spelling | doaj.art-a32780a2411d4c15acc300d6d5ff92592022-12-22T03:44:04ZengFrontiers Media S.A.Frontiers in Behavioral Neuroscience1662-51532015-06-01910.3389/fnbeh.2015.00147141722Neuroplastic effects of transcranial near-infrared stimulation (tNIRS) on the motor cortexLeila eChaieb0Andrea eAntal1Florentin eMasurat2Walter ePaulus3University of BonnUniversity Medical Center GoettingenUniversity Medical Center GoettingenUniversity Medical Center GoettingenNear-infrared light stimulation of the brain has been claimed to improve deficits caused by traumatic brain injury and stroke. Here, we exploit the effect of transcranial near-infrared stimulation (tNIRS) as a tool to modulate cortical excitability in the healthy human brain. tNIRS was applied at a wavelength of 810 nm for 10 minutes over the hand area of the primary motor cortex (M1). Both single-pulse and paired-pulse measures of transcranial magnetic stimulation (TMS) were used to assess levels of cortical excitability in the corticospinal pathway and intracortical circuits. The serial reaction time task (SRTT) was used to investigate the possible effect of tNIRS on implicit learning.By evaluating the mean amplitude of single-pulse TMS elicited motor-evoked-potentials (MEPs) a significant decrease of the amplitude was observed up to 30 minutes post-stimulation, compared to baseline. Furthermore, the short interval cortical inhibition (SICI) was increased and facilitation (ICF) decreased significantly after tNIRS. The results from the SRTT experiment show that there was no net effect of stimulation on the performance of the participants. Results of a study questionnaire demonstrated that tNIRS did not induce serious side effects apart from light headache and fatigue. Nevertheless, 66% were able to detect the difference between active and sham stimulation conditions.In this study we provide further evidence that tNIRS is suitable as a tool for influencing cortical excitability and activity in the healthy human brain.http://journal.frontiersin.org/Journal/10.3389/fnbeh.2015.00147/fullBrainLearninghumanneuroplasticitytranscranial near-infrared laser light stimulation |
| spellingShingle | Leila eChaieb Andrea eAntal Florentin eMasurat Walter ePaulus Neuroplastic effects of transcranial near-infrared stimulation (tNIRS) on the motor cortex Frontiers in Behavioral Neuroscience Brain Learning human neuroplasticity transcranial near-infrared laser light stimulation |
| title | Neuroplastic effects of transcranial near-infrared stimulation (tNIRS) on the motor cortex |
| title_full | Neuroplastic effects of transcranial near-infrared stimulation (tNIRS) on the motor cortex |
| title_fullStr | Neuroplastic effects of transcranial near-infrared stimulation (tNIRS) on the motor cortex |
| title_full_unstemmed | Neuroplastic effects of transcranial near-infrared stimulation (tNIRS) on the motor cortex |
| title_short | Neuroplastic effects of transcranial near-infrared stimulation (tNIRS) on the motor cortex |
| title_sort | neuroplastic effects of transcranial near infrared stimulation tnirs on the motor cortex |
| topic | Brain Learning human neuroplasticity transcranial near-infrared laser light stimulation |
| url | http://journal.frontiersin.org/Journal/10.3389/fnbeh.2015.00147/full |
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