The transacting factor CBF-A/Hnrnpab binds to the A2RE/RTS element of protamine 2 mRNA and contributes to its translational regulation during mouse spermatogenesis.
During spermatogenesis, mRNA localization and translation are believed to be regulated in a stage-specific manner. We report here that the Protamine2 (Prm2) mRNA transits through chromatoid bodies of round spermatids and localizes to cytosol of elongating spermatids for translation. The transacting...
Main Authors: | , , , , , , , |
---|---|
格式: | 文件 |
语言: | English |
出版: |
Public Library of Science (PLoS)
2013-01-01
|
丛编: | PLoS Genetics |
在线阅读: | http://europepmc.org/articles/PMC3798277?pdf=render |