Potential Benefits of Probiotics and Prebiotics for Coronary Heart Disease and Stroke
Among cardiovascular diseases (CVDs), a major cause of morbidity and mortality worldwide, coronary heart disease and stroke are the most well-known and extensively studied. The onset and progression of CVD is associated with multiple risk factors, among which, gut microbiota has received much attent...
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| Format: | Article |
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MDPI AG
2021-08-01
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| Series: | Nutrients |
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| Online Access: | https://www.mdpi.com/2072-6643/13/8/2878 |
| _version_ | 1797522510602829824 |
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| author | Haicui Wu Jiachi Chiou |
| author_facet | Haicui Wu Jiachi Chiou |
| author_sort | Haicui Wu |
| collection | DOAJ |
| description | Among cardiovascular diseases (CVDs), a major cause of morbidity and mortality worldwide, coronary heart disease and stroke are the most well-known and extensively studied. The onset and progression of CVD is associated with multiple risk factors, among which, gut microbiota has received much attention in the past two decades. Gut microbiota, the microbial community colonizing in the gut, plays a prominent role in human health. In particular, gut dysbiosis is directly related to many acute or chronic dysfunctions of the cardiovascular system (CVS) in the host. Earlier studies have demonstrated that the pathogenesis of CVD is strongly linked to intestinal microbiota imbalance and inflammatory responses. Probiotics and prebiotics conferring various health benefits on the host are emerging as promising therapeutic interventions for many diseases. These two types of food supplements have the potential to alleviate the risks of CVD through improving the levels of several cardiovascular markers, such as total and low-density lipoprotein (LDL) cholesterol, high sensitivity C-reactive protein (hs-CRP), and certain cytokines involved in the inflammatory response. In this review, we focus mainly on the preventive effects of probiotics and prebiotics on CVD via rebalancing the structural and functional changes in gut microbiota and maintaining immune homeostasis. |
| first_indexed | 2024-03-10T08:30:25Z |
| format | Article |
| id | doaj.art-a32cf899affa4203b5cae51c711a2f45 |
| institution | Directory Open Access Journal |
| issn | 2072-6643 |
| language | English |
| last_indexed | 2024-03-10T08:30:25Z |
| publishDate | 2021-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nutrients |
| spelling | doaj.art-a32cf899affa4203b5cae51c711a2f452023-11-22T09:07:29ZengMDPI AGNutrients2072-66432021-08-01138287810.3390/nu13082878Potential Benefits of Probiotics and Prebiotics for Coronary Heart Disease and StrokeHaicui Wu0Jiachi Chiou1Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, ChinaDepartment of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, ChinaAmong cardiovascular diseases (CVDs), a major cause of morbidity and mortality worldwide, coronary heart disease and stroke are the most well-known and extensively studied. The onset and progression of CVD is associated with multiple risk factors, among which, gut microbiota has received much attention in the past two decades. Gut microbiota, the microbial community colonizing in the gut, plays a prominent role in human health. In particular, gut dysbiosis is directly related to many acute or chronic dysfunctions of the cardiovascular system (CVS) in the host. Earlier studies have demonstrated that the pathogenesis of CVD is strongly linked to intestinal microbiota imbalance and inflammatory responses. Probiotics and prebiotics conferring various health benefits on the host are emerging as promising therapeutic interventions for many diseases. These two types of food supplements have the potential to alleviate the risks of CVD through improving the levels of several cardiovascular markers, such as total and low-density lipoprotein (LDL) cholesterol, high sensitivity C-reactive protein (hs-CRP), and certain cytokines involved in the inflammatory response. In this review, we focus mainly on the preventive effects of probiotics and prebiotics on CVD via rebalancing the structural and functional changes in gut microbiota and maintaining immune homeostasis.https://www.mdpi.com/2072-6643/13/8/2878CVDprobioticsprebioticsgut microbiotaimmune homeostasis |
| spellingShingle | Haicui Wu Jiachi Chiou Potential Benefits of Probiotics and Prebiotics for Coronary Heart Disease and Stroke Nutrients CVD probiotics prebiotics gut microbiota immune homeostasis |
| title | Potential Benefits of Probiotics and Prebiotics for Coronary Heart Disease and Stroke |
| title_full | Potential Benefits of Probiotics and Prebiotics for Coronary Heart Disease and Stroke |
| title_fullStr | Potential Benefits of Probiotics and Prebiotics for Coronary Heart Disease and Stroke |
| title_full_unstemmed | Potential Benefits of Probiotics and Prebiotics for Coronary Heart Disease and Stroke |
| title_short | Potential Benefits of Probiotics and Prebiotics for Coronary Heart Disease and Stroke |
| title_sort | potential benefits of probiotics and prebiotics for coronary heart disease and stroke |
| topic | CVD probiotics prebiotics gut microbiota immune homeostasis |
| url | https://www.mdpi.com/2072-6643/13/8/2878 |
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