Pott’s paraplegia and role of neuroimaging in resource limited setting: A case report and brief review of the literatures
Background: Tuberculosis (TB) is the leading cause of morbidity and mortality in low and middle income countries (LMIC). Approximately 50% of cases of skeletal TB involve the spine. Failure to identify and treat these areas of involvement at an early stage may lead to serious complications such as v...
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| Format: | Article |
| Language: | English |
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Elsevier
2021-12-01
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| Series: | Journal of Clinical Tuberculosis and Other Mycobacterial Diseases |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405579421000723 |
| _version_ | 1818399671122395136 |
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| author | Biniyam A. Ayele Abdinasir Wako Jarso Tadesse Hildana Gulelat Riyad Ibrahim Sisay Molla Abdi Bati |
| author_facet | Biniyam A. Ayele Abdinasir Wako Jarso Tadesse Hildana Gulelat Riyad Ibrahim Sisay Molla Abdi Bati |
| author_sort | Biniyam A. Ayele |
| collection | DOAJ |
| description | Background: Tuberculosis (TB) is the leading cause of morbidity and mortality in low and middle income countries (LMIC). Approximately 50% of cases of skeletal TB involve the spine. Failure to identify and treat these areas of involvement at an early stage may lead to serious complications such as vertebral collapse, spinal compression, and spinal deformity. The clinical and radiologic features of Pott’s disease may mimic other spine diseases such as, metastatic lesions and other infectious etiologies, this is especially imperative in older patients. Case report: We report a 60-year-old right handed male patient presented with back pain, paraparesis, and sensory symptoms 2 weeks duration. He has history of dry cough, fatigue, and reduced appetite, but no history of weight loss, fever, night sweat, and bowel/bladder incontinence. No contact history with TB patients. He has a borderline hypertension and diabetes mellitus. Serology for HIV was negative. Thoraco-lumbar magnetic resonance image (MRI) showed destruction of L2 and L3 vertebral body and the inter-vertebral disc; with T2 hyper and T1 hypointensity of the affected vertebral bodies. Probable tuberculous spondylitis with paraparesis was considered and the patient was initiated on antituberculous regimen and short course steroid therapy. After five months treatment, the patient showed significant clinical and radiological improvement. Conclusion: In summary, the present case describes, a patient with Pott’s paraplegia due to probable spine tuberculosis and showed significant clinical and radiological improvement following initiation of antituberculous drugs and short course of steroid; indicating the crucial role of imaging in the diagnosis of TB, especially in resource limited settings. |
| first_indexed | 2024-12-14T07:24:23Z |
| format | Article |
| id | doaj.art-a32d36f6a92046be865513254095f9e4 |
| institution | Directory Open Access Journal |
| issn | 2405-5794 |
| language | English |
| last_indexed | 2024-12-14T07:24:23Z |
| publishDate | 2021-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Clinical Tuberculosis and Other Mycobacterial Diseases |
| spelling | doaj.art-a32d36f6a92046be865513254095f9e42022-12-21T23:11:33ZengElsevierJournal of Clinical Tuberculosis and Other Mycobacterial Diseases2405-57942021-12-0125100283Pott’s paraplegia and role of neuroimaging in resource limited setting: A case report and brief review of the literaturesBiniyam A. Ayele0Abdinasir Wako1Jarso Tadesse2Hildana Gulelat3Riyad Ibrahim4Sisay Molla5Abdi Bati6Department of Neurology, Addis Ababa University, Addis Ababa, Ethiopia; Corresponding author at: Department of Neurology, School of Medicine, College of Health Sciences, Addis Ababa University, Addis Ababa PoBox 6396, Ethiopia.School of Medicine, Jijiga University, Jijiga, EthiopiaSchool of Medicine, Dilla University, Dilla, EthiopiaYehuleshet Specialty Clinic, Addis Ababa, EthiopiaSchool of Medicine, Wolkite University, Wolkite, EthiopiaDepartment of Internal Medicine, Haramaya University, Harar, EthiopiaMedicine and Hepatology and Gastroenterology ALERT Hospital, Addis Ababa, EthiopiaBackground: Tuberculosis (TB) is the leading cause of morbidity and mortality in low and middle income countries (LMIC). Approximately 50% of cases of skeletal TB involve the spine. Failure to identify and treat these areas of involvement at an early stage may lead to serious complications such as vertebral collapse, spinal compression, and spinal deformity. The clinical and radiologic features of Pott’s disease may mimic other spine diseases such as, metastatic lesions and other infectious etiologies, this is especially imperative in older patients. Case report: We report a 60-year-old right handed male patient presented with back pain, paraparesis, and sensory symptoms 2 weeks duration. He has history of dry cough, fatigue, and reduced appetite, but no history of weight loss, fever, night sweat, and bowel/bladder incontinence. No contact history with TB patients. He has a borderline hypertension and diabetes mellitus. Serology for HIV was negative. Thoraco-lumbar magnetic resonance image (MRI) showed destruction of L2 and L3 vertebral body and the inter-vertebral disc; with T2 hyper and T1 hypointensity of the affected vertebral bodies. Probable tuberculous spondylitis with paraparesis was considered and the patient was initiated on antituberculous regimen and short course steroid therapy. After five months treatment, the patient showed significant clinical and radiological improvement. Conclusion: In summary, the present case describes, a patient with Pott’s paraplegia due to probable spine tuberculosis and showed significant clinical and radiological improvement following initiation of antituberculous drugs and short course of steroid; indicating the crucial role of imaging in the diagnosis of TB, especially in resource limited settings.http://www.sciencedirect.com/science/article/pii/S2405579421000723Pott’s paraplegiaTuberculosisSpinal tuberculosisAnti-tuberculous drugsEthiopia |
| spellingShingle | Biniyam A. Ayele Abdinasir Wako Jarso Tadesse Hildana Gulelat Riyad Ibrahim Sisay Molla Abdi Bati Pott’s paraplegia and role of neuroimaging in resource limited setting: A case report and brief review of the literatures Journal of Clinical Tuberculosis and Other Mycobacterial Diseases Pott’s paraplegia Tuberculosis Spinal tuberculosis Anti-tuberculous drugs Ethiopia |
| title | Pott’s paraplegia and role of neuroimaging in resource limited setting: A case report and brief review of the literatures |
| title_full | Pott’s paraplegia and role of neuroimaging in resource limited setting: A case report and brief review of the literatures |
| title_fullStr | Pott’s paraplegia and role of neuroimaging in resource limited setting: A case report and brief review of the literatures |
| title_full_unstemmed | Pott’s paraplegia and role of neuroimaging in resource limited setting: A case report and brief review of the literatures |
| title_short | Pott’s paraplegia and role of neuroimaging in resource limited setting: A case report and brief review of the literatures |
| title_sort | pott s paraplegia and role of neuroimaging in resource limited setting a case report and brief review of the literatures |
| topic | Pott’s paraplegia Tuberculosis Spinal tuberculosis Anti-tuberculous drugs Ethiopia |
| url | http://www.sciencedirect.com/science/article/pii/S2405579421000723 |
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