AUF-1 knockdown in mice undermines gut microbial butyrate-driven hypocholesterolemia through AUF-1–Dicer-1–mir-122 hierarchy

AUF-1 knockdown in mice undermines gut microbial butyrate-driven hypocholesterolemia through AUF-1–Dicer-1–mir-122 hierarchy

Introduction and objectiveCholesterol homeostasis is a culmination of cellular synthesis, efflux, and catabolism to important physiological entities where short chain fatty acid, butyrate embodied as a key player. This discourse probes the mechanistic molecular details of butyrate action in maintain...

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Bibliographic Details
Main Authors: Oishika Das, Jayanta Kundu, Atanu Ghosh, Anupam Gautam, Souradeepa Ghosh, Mainak Chakraborty, Aaheli Masid, Samiran Sona Gauri, Debmalya Mitra, Moumita Dutta, Budhaditya Mukherjee, Surajit Sinha, Moumita Bhaumik
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
AUF-1
butyrate
cholesterol metabolism
Dicer-1
GMO–PMO
microbiome
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2022.1011386/full

Internet

https://www.frontiersin.org/articles/10.3389/fcimb.2022.1011386/full

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