Mitochondrial DNA sequencing of Kehilan and Hamdani horses from Saudi Arabia
The Arabian horse breed is well known for its purity and played a key role in the genetic improvement of other horses worldwide. The mitochondrial genome plays a vital role in maternal inheritance and it’s helpful to evaluate its genetic diversity and conservation. It has higher mutation rates than...
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| Format: | Article |
| Language: | English |
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Elsevier
2023-09-01
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| Series: | Saudi Journal of Biological Sciences |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1319562X23001869 |
| _version_ | 1797690945141997568 |
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| author | Abdullah Sheikh |
| author_facet | Abdullah Sheikh |
| author_sort | Abdullah Sheikh |
| collection | DOAJ |
| description | The Arabian horse breed is well known for its purity and played a key role in the genetic improvement of other horses worldwide. The mitochondrial genome plays a vital role in maternal inheritance and it’s helpful to evaluate its genetic diversity and conservation. It has higher mutation rates than nuclear DNA in vertebrates and therefore reveals phylogenetic relationships and haplotypes. In this study, the mitochondrial genome mutations in two Saudi horse strains, Kehilan and Hamdani demonstrated various changes in the gene and amino acid levels and included two other Saudi horses (Hadban and Seglawi) from the previous study for phylogenetic comparison. The whole mitochondrial genome sequencing resulted in intra and inter mtDNA variations between the studied horses. Interestingly, the Hamdani horse has nucleotide substitutions similar to those of the Hadban horse, which is reflected in the phylogenetic tree as a significantly close relationship. This type of study provides a better understanding of mitogenome structure and conservation of livestock species genetic data. |
| first_indexed | 2024-03-12T02:06:24Z |
| format | Article |
| id | doaj.art-a3342a71347b4f2e96c0659856eadce5 |
| institution | Directory Open Access Journal |
| issn | 1319-562X |
| language | English |
| last_indexed | 2024-03-12T02:06:24Z |
| publishDate | 2023-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Saudi Journal of Biological Sciences |
| spelling | doaj.art-a3342a71347b4f2e96c0659856eadce52023-09-07T04:43:12ZengElsevierSaudi Journal of Biological Sciences1319-562X2023-09-01309103741Mitochondrial DNA sequencing of Kehilan and Hamdani horses from Saudi ArabiaAbdullah Sheikh0Camel Research Center, King Faisal University, P.O. Box 400, Al-Ahsa 31982, Saudi ArabiaThe Arabian horse breed is well known for its purity and played a key role in the genetic improvement of other horses worldwide. The mitochondrial genome plays a vital role in maternal inheritance and it’s helpful to evaluate its genetic diversity and conservation. It has higher mutation rates than nuclear DNA in vertebrates and therefore reveals phylogenetic relationships and haplotypes. In this study, the mitochondrial genome mutations in two Saudi horse strains, Kehilan and Hamdani demonstrated various changes in the gene and amino acid levels and included two other Saudi horses (Hadban and Seglawi) from the previous study for phylogenetic comparison. The whole mitochondrial genome sequencing resulted in intra and inter mtDNA variations between the studied horses. Interestingly, the Hamdani horse has nucleotide substitutions similar to those of the Hadban horse, which is reflected in the phylogenetic tree as a significantly close relationship. This type of study provides a better understanding of mitogenome structure and conservation of livestock species genetic data.http://www.sciencedirect.com/science/article/pii/S1319562X23001869MitochondriaArabian horseSingle nucleotide polymorphismsCoding regionPhylogeny |
| spellingShingle | Abdullah Sheikh Mitochondrial DNA sequencing of Kehilan and Hamdani horses from Saudi Arabia Saudi Journal of Biological Sciences Mitochondria Arabian horse Single nucleotide polymorphisms Coding region Phylogeny |
| title | Mitochondrial DNA sequencing of Kehilan and Hamdani horses from Saudi Arabia |
| title_full | Mitochondrial DNA sequencing of Kehilan and Hamdani horses from Saudi Arabia |
| title_fullStr | Mitochondrial DNA sequencing of Kehilan and Hamdani horses from Saudi Arabia |
| title_full_unstemmed | Mitochondrial DNA sequencing of Kehilan and Hamdani horses from Saudi Arabia |
| title_short | Mitochondrial DNA sequencing of Kehilan and Hamdani horses from Saudi Arabia |
| title_sort | mitochondrial dna sequencing of kehilan and hamdani horses from saudi arabia |
| topic | Mitochondria Arabian horse Single nucleotide polymorphisms Coding region Phylogeny |
| url | http://www.sciencedirect.com/science/article/pii/S1319562X23001869 |
| work_keys_str_mv | AT abdullahsheikh mitochondrialdnasequencingofkehilanandhamdanihorsesfromsaudiarabia |