Antillatoxin is a sodium channel activator that displays unique efficacy in heterologously expressed rNa<sub>v</sub>1.2, rNa<sub>v</sub>1.4 and rNa<sub>v</sub>1.5 alpha subunits
<p>Abstract</p> <p>Background</p> <p>Antillatoxin (ATX) is a structurally unique lipopeptide produced by the marine cyanobacterium <it>Lyngbya majuscula</it>. ATX activates voltage-gated sodium channel α-subunits at an undefined recognition site and stimulat...
Main Authors: | Gerwick William H, Cao Zhengyu, Murray Thomas F |
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Format: | Article |
Language: | English |
Published: |
BMC
2010-12-01
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Series: | BMC Neuroscience |
Online Access: | http://www.biomedcentral.com/1471-2202/11/154 |
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