USP5 knockdown alleviates lung cancer progression via activating PARP1-mediated mTOR signaling pathway

USP5 knockdown alleviates lung cancer progression via activating PARP1-mediated mTOR signaling pathway

Abstract Background With the rapidly increasing morbidity and mortality, lung cancer has been considered one of the serious malignant tumors, affecting millions of patients globally. Currently, the pathogenesis of lung cancer remains unclear, hindering the development of effective treatment. This st...

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Bibliographic Details
Main Authors: Lei Cao, Hongsheng Liu, Cheng Huang, Chao Guo, Luo Zhao, Chao Gao, Yuan Xu, Guige Wang, Naixin Liang, Shanqing Li
Format: Article
Language:English
Published: BMC 2023-04-01
Series:Biology Direct
Subjects:
USP5
mTOR
PARP1
Lung cancer
Online Access:https://doi.org/10.1186/s13062-023-00371-z

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