Silymarin Protects against Acute Liver Injury Induced by Acetaminophen by Downregulating the Expression and Activity of the CYP2E1 Enzyme

Silymarin Protects against Acute Liver Injury Induced by Acetaminophen by Downregulating the Expression and Activity of the CYP2E1 Enzyme

Previous studies have shown that silymarin protects against various types of drug-induced liver injury, but whether the protective mechanism of silymarin against acetaminophen-induced liver injury is related to the CYP2E1 enzyme remains unclear. In this study, we investigated the effect of silymarin...

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Bibliographic Details
Main Authors:	Weipei Yang, Zhongxu Liang, Chengming Wen, Xuehua Jiang, Ling Wang
Format:	Article
Language:	English
Published:	MDPI AG 2022-12-01
Series:	Molecules
Subjects:	silymarin acetaminophen CYP2E1 acute liver injury
Online Access:	https://www.mdpi.com/1420-3049/27/24/8855

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