Fas Signaling Promotes Gastric Cancer Metastasis through STAT3-Dependent Upregulation of Fascin.

Fas signaling-activated signal transducers and activators of transcription 3 (STAT3) is required for Fascin upregulation. As an actin-bundling protein, Fascin can mediate gastric cancer (GC) cell migration.Gastric cancer AGS cells were treated with anti-Fas (5 μg/ml) for 2 h, in order to stimulate t...

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Váldodahkkit: Yunshan Yang, Qiyu Zhao, Zhijian Cai, Guoping Cheng, Ming Chen, Jiaoli Wang, Haijun Zhong
Materiálatiipa: Artihkal
Giella:English
Almmustuhtton: Public Library of Science (PLoS) 2015-01-01
Ráidu:PLoS ONE
Liŋkkat:http://europepmc.org/articles/PMC4436300?pdf=render