Tumor-derived exosomes promote the in vitro osteotropism of melanoma cells by activating the SDF-1/CXCR4/CXCR7 axis
Abstract Background Bone metastases occur rarely in patients suffering from malignant melanoma, although their onset severely worsens both prognosis and quality of life. Extracellular vesicles (EVs) including exosomes (Exos) are active players in melanoma progression involved in the formation of the...
| Main Authors: | , , , , , |
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| 格式: | Article |
| 語言: | English |
| 出版: |
BMC
2019-07-01
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| 叢編: | Journal of Translational Medicine |
| 主題: | |
| 在線閱讀: | http://link.springer.com/article/10.1186/s12967-019-1982-4 |