Systems Network Genomic Analysis Reveals Cardioprotective Effect of MURC/Cavin‐4 Deletion Against Ischemia/Reperfusion Injury

Systems Network Genomic Analysis Reveals Cardioprotective Effect of MURC/Cavin‐4 Deletion Against Ischemia/Reperfusion Injury

Background Ischemia/reperfusion (I/R) injury is a critical issue in the development of treatment strategies for ischemic heart disease. MURC (muscle‐restricted coiled‐coil protein)/Cavin‐4 (caveolae‐associated protein 4), which is a component of caveolae, is involved in the pathophysiology of dilate...

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Bibliographic Details
Main Authors: Masahiro Nishi, Takehiro Ogata, Carlo Vittorio Cannistraci, Sara Ciucci, Naohiko Nakanishi, Yusuke Higuchi, Akira Sakamoto, Yumika Tsuji, Katsura Mizushima, Satoaki Matoba
Format: Article
Language:English
Published: Wiley 2019-08-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
apoptosis
caveolae
ischemia reperfusion injury
reactive oxygen species
systems biology
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.119.012047

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