Cigarette Smoking Preferentially Affects Intracranial Vessels in Young Males: A Propensity-Score Matching Analysis
Purpose Cigarette smoking (CS) is one of the major risk factors of cerebral atherosclerotic disease, however, its level of contribution to extracranial and intracranial atherosclerotic stenosis (ECAS and ICAS) was not fully revealed yet. The purpose of our study was to assess the association of CS t...
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| Format: | Article |
| Language: | English |
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Korean Society of Interventional Neuroradiology
2019-03-01
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| Series: | Neurointervention |
| Subjects: | |
| Online Access: | http://neurointervention.org/upload/pdf/neuroint-2018-01123.pdf |
| _version_ | 1827364158168891392 |
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| author | Yunsun Song Dongwhane Lee Dae Chul Suh Joong-goo Kim Jae Kyun Kim Minkyu Han Hairi Liu Lingbo Zhao Eun Hye Kim Sung Chul Jung Dong-geun Lee Hyun Jung Koo Min-ju Kim Seunghee Baek Seon Moon Hwang Bum Joon Kim Yeon-Jung Kim Hong-Jun Cho Sang Joon Kim Sang-Beom Jeon Jong S. Kim |
| author_facet | Yunsun Song Dongwhane Lee Dae Chul Suh Joong-goo Kim Jae Kyun Kim Minkyu Han Hairi Liu Lingbo Zhao Eun Hye Kim Sung Chul Jung Dong-geun Lee Hyun Jung Koo Min-ju Kim Seunghee Baek Seon Moon Hwang Bum Joon Kim Yeon-Jung Kim Hong-Jun Cho Sang Joon Kim Sang-Beom Jeon Jong S. Kim |
| author_sort | Yunsun Song |
| collection | DOAJ |
| description | Purpose Cigarette smoking (CS) is one of the major risk factors of cerebral atherosclerotic disease, however, its level of contribution to extracranial and intracranial atherosclerotic stenosis (ECAS and ICAS) was not fully revealed yet. The purpose of our study was to assess the association of CS to cerebral atherosclerosis along with other risk factors. Materials and Methods All consecutive patients who were angiographically confirmed with severe symptomatic cerebral atherosclerotic disease between January 2002 and December 2012 were included in this study. Multivariate logistic regression analyses were performed to identify risk factors for ECAS and ICAS. Thereafter, CS group were compared to non-CS group in the entire study population and in a propensity-score matched population with two different age-subgroups. Results Of 1709 enrolled patients, 794 (46.5%) had extracranial (EC) lesions and the other 915 (53.5%) had intracranial (IC) lesions. CS group had more EC lesions (55.8% vs. 35.3%, P<0.001) whereas young age group (<50 years) had more IC lesion (84.5% vs. 47.6%, P<0.001). In multivariate analysis, seven variables including CS, male, old age, coronary heart disease, higher erythrocyte sedimentation rate, multiple lesions, and anterior lesion were independently associated with ECAS. In the propensity-score matched CS group had significant more EC lesion compared to non-CS group (65.7% vs. 47.9%) only in the old age subgroup. Conclusion In contrast to a significant association between CS and severe symptomatic ECAS shown in old population, young patients did not show this association and showed relatively higher preference of ICAS. |
| first_indexed | 2024-03-08T08:03:47Z |
| format | Article |
| id | doaj.art-a34873fa45b24698a3ed5dcd12e0a1b8 |
| institution | Directory Open Access Journal |
| issn | 2093-9043 2233-6273 |
| language | English |
| last_indexed | 2024-03-08T08:03:47Z |
| publishDate | 2019-03-01 |
| publisher | Korean Society of Interventional Neuroradiology |
| record_format | Article |
| series | Neurointervention |
| spelling | doaj.art-a34873fa45b24698a3ed5dcd12e0a1b82024-02-02T11:37:55ZengKorean Society of Interventional NeuroradiologyNeurointervention2093-90432233-62732019-03-01141435210.5469/neuroint.2018.01123258Cigarette Smoking Preferentially Affects Intracranial Vessels in Young Males: A Propensity-Score Matching AnalysisYunsun Song0Dongwhane Lee1Dae Chul Suh2Joong-goo Kim3Jae Kyun Kim4Minkyu Han5Hairi Liu6Lingbo Zhao7Eun Hye Kim8Sung Chul Jung9Dong-geun Lee10Hyun Jung Koo11Min-ju Kim12Seunghee Baek13Seon Moon Hwang14Bum Joon Kim15Yeon-Jung Kim16Hong-Jun Cho17Sang Joon Kim18Sang-Beom Jeon19Jong S. Kim20 Department of Radiology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea Department of Neurology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea Department of Radiology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea Department of Neurology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea Department of Radiology, Chung-Ang University College of Medicine, Seoul, Korea Department of Clinical Epidemiology and Biostatistics, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea Department of Interventional Radiology, Taizhou People’s Hospital, Taizhou, China Department of Radiology, First Affiliated Hospital of Nanjing Medical University, Nanjing, China Department of Radiology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea Department of Radiology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea Department of Radiology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea Department of Radiology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea Department of Clinical Epidemiology and Biostatistics, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea Department of Clinical Epidemiology and Biostatistics, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea Department of Radiology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea Department of Neurology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea Department of Neurology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea Department of Family Medicine, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea Department of Radiology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea Department of Neurology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea Department of Neurology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, KoreaPurpose Cigarette smoking (CS) is one of the major risk factors of cerebral atherosclerotic disease, however, its level of contribution to extracranial and intracranial atherosclerotic stenosis (ECAS and ICAS) was not fully revealed yet. The purpose of our study was to assess the association of CS to cerebral atherosclerosis along with other risk factors. Materials and Methods All consecutive patients who were angiographically confirmed with severe symptomatic cerebral atherosclerotic disease between January 2002 and December 2012 were included in this study. Multivariate logistic regression analyses were performed to identify risk factors for ECAS and ICAS. Thereafter, CS group were compared to non-CS group in the entire study population and in a propensity-score matched population with two different age-subgroups. Results Of 1709 enrolled patients, 794 (46.5%) had extracranial (EC) lesions and the other 915 (53.5%) had intracranial (IC) lesions. CS group had more EC lesions (55.8% vs. 35.3%, P<0.001) whereas young age group (<50 years) had more IC lesion (84.5% vs. 47.6%, P<0.001). In multivariate analysis, seven variables including CS, male, old age, coronary heart disease, higher erythrocyte sedimentation rate, multiple lesions, and anterior lesion were independently associated with ECAS. In the propensity-score matched CS group had significant more EC lesion compared to non-CS group (65.7% vs. 47.9%) only in the old age subgroup. Conclusion In contrast to a significant association between CS and severe symptomatic ECAS shown in old population, young patients did not show this association and showed relatively higher preference of ICAS.http://neurointervention.org/upload/pdf/neuroint-2018-01123.pdfatherosclerosisrisk factorscerebrovascular circulationsmoking |
| spellingShingle | Yunsun Song Dongwhane Lee Dae Chul Suh Joong-goo Kim Jae Kyun Kim Minkyu Han Hairi Liu Lingbo Zhao Eun Hye Kim Sung Chul Jung Dong-geun Lee Hyun Jung Koo Min-ju Kim Seunghee Baek Seon Moon Hwang Bum Joon Kim Yeon-Jung Kim Hong-Jun Cho Sang Joon Kim Sang-Beom Jeon Jong S. Kim Cigarette Smoking Preferentially Affects Intracranial Vessels in Young Males: A Propensity-Score Matching Analysis Neurointervention atherosclerosis risk factors cerebrovascular circulation smoking |
| title | Cigarette Smoking Preferentially Affects Intracranial Vessels in Young Males: A Propensity-Score Matching Analysis |
| title_full | Cigarette Smoking Preferentially Affects Intracranial Vessels in Young Males: A Propensity-Score Matching Analysis |
| title_fullStr | Cigarette Smoking Preferentially Affects Intracranial Vessels in Young Males: A Propensity-Score Matching Analysis |
| title_full_unstemmed | Cigarette Smoking Preferentially Affects Intracranial Vessels in Young Males: A Propensity-Score Matching Analysis |
| title_short | Cigarette Smoking Preferentially Affects Intracranial Vessels in Young Males: A Propensity-Score Matching Analysis |
| title_sort | cigarette smoking preferentially affects intracranial vessels in young males a propensity score matching analysis |
| topic | atherosclerosis risk factors cerebrovascular circulation smoking |
| url | http://neurointervention.org/upload/pdf/neuroint-2018-01123.pdf |
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