Mitochondrial Retrograde Signalling and Metabolic Alterations in the Tumour Microenvironment

This review explores the molecular mechanisms that may be responsible for mitochondrial retrograde signalling related metabolic reprogramming in cancer and host cells in the tumour microenvironment and provides a summary of recent updates with regard to the functional modulation of diverse cells in...

Full description

Bibliographic Details
Main Authors: Dongki Yang, Jaehong Kim
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/8/3/275
_version_ 1797713233480515584
author Dongki Yang
Jaehong Kim
author_facet Dongki Yang
Jaehong Kim
author_sort Dongki Yang
collection DOAJ
description This review explores the molecular mechanisms that may be responsible for mitochondrial retrograde signalling related metabolic reprogramming in cancer and host cells in the tumour microenvironment and provides a summary of recent updates with regard to the functional modulation of diverse cells in the tumour microenvironment.
first_indexed 2024-03-12T07:33:23Z
format Article
id doaj.art-a3492b7676de42e4ae48d1873c0a432a
institution Directory Open Access Journal
issn 2073-4409
language English
last_indexed 2024-03-12T07:33:23Z
publishDate 2019-03-01
publisher MDPI AG
record_format Article
series Cells
spelling doaj.art-a3492b7676de42e4ae48d1873c0a432a2023-09-02T21:40:55ZengMDPI AGCells2073-44092019-03-018327510.3390/cells8030275cells8030275Mitochondrial Retrograde Signalling and Metabolic Alterations in the Tumour MicroenvironmentDongki Yang0Jaehong Kim1Department of Physiology, College of Medicine, Gachon University, Incheon 21999, KoreaDepartment of Biochemistry, College of Medicine, Gachon University, Incheon 21999, KoreaThis review explores the molecular mechanisms that may be responsible for mitochondrial retrograde signalling related metabolic reprogramming in cancer and host cells in the tumour microenvironment and provides a summary of recent updates with regard to the functional modulation of diverse cells in the tumour microenvironment.https://www.mdpi.com/2073-4409/8/3/275mitochondriaretrograde signallingmetabolic reprogrammingtumour microenvironmentEMT
spellingShingle Dongki Yang
Jaehong Kim
Mitochondrial Retrograde Signalling and Metabolic Alterations in the Tumour Microenvironment
Cells
mitochondria
retrograde signalling
metabolic reprogramming
tumour microenvironment
EMT
title Mitochondrial Retrograde Signalling and Metabolic Alterations in the Tumour Microenvironment
title_full Mitochondrial Retrograde Signalling and Metabolic Alterations in the Tumour Microenvironment
title_fullStr Mitochondrial Retrograde Signalling and Metabolic Alterations in the Tumour Microenvironment
title_full_unstemmed Mitochondrial Retrograde Signalling and Metabolic Alterations in the Tumour Microenvironment
title_short Mitochondrial Retrograde Signalling and Metabolic Alterations in the Tumour Microenvironment
title_sort mitochondrial retrograde signalling and metabolic alterations in the tumour microenvironment
topic mitochondria
retrograde signalling
metabolic reprogramming
tumour microenvironment
EMT
url https://www.mdpi.com/2073-4409/8/3/275
work_keys_str_mv AT dongkiyang mitochondrialretrogradesignallingandmetabolicalterationsinthetumourmicroenvironment
AT jaehongkim mitochondrialretrogradesignallingandmetabolicalterationsinthetumourmicroenvironment