CRYO-RADIOTHERAPY FOR LOCAL LYADVANCED RECURRENT SKIN CANCER OF THE FACE
The aim of the study was to improve the treatment outcomes for patients with locally advanced recurrent basal cell and squamous cell skin carcinomas of the face. Material and methods. A total of 26 patients with locally advanced recurrent basal cell (n=21) and squamous cell (n=5) skin carcinomas of...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
Russian Academy of Sciences, Tomsk National Research Medical Center
2017-12-01
|
| Series: | Сибирский онкологический журнал |
| Subjects: | |
| Online Access: | https://www.siboncoj.ru/jour/article/view/643 |
| _version_ | 1826563768217239552 |
|---|---|
| author | I. N. Pustynskiy T. D. Tabolinovskaya S. I. Tkachev S. B. Alieva R. I. Azizian E. V. Kiva A. V. Egorova S. B. Peterson |
| author_facet | I. N. Pustynskiy T. D. Tabolinovskaya S. I. Tkachev S. B. Alieva R. I. Azizian E. V. Kiva A. V. Egorova S. B. Peterson |
| author_sort | I. N. Pustynskiy |
| collection | DOAJ |
| description | The aim of the study was to improve the treatment outcomes for patients with locally advanced recurrent basal cell and squamous cell skin carcinomas of the face. Material and methods. A total of 26 patients with locally advanced recurrent basal cell (n=21) and squamous cell (n=5) skin carcinomas of the skin were treated with radiotherapy (2–2.5 Gy daily fractions to a total dose of 60–70 Gy, 5 days a week) in combination with local freezing of the tumor. Local cooling of the tumor to the temperature of tissue freezing was performed 10–15 minutes before each session of radiation therapy using liquid nitrogen cryo-preservation equipment. Patients with recurrent skin cancer who had received previously radiation therapy were not eligible for cryoradiotherapy. Results. Complete response was achieved in 23 (88.5 %) patients, residual tumors were removed by conventional surgery (n=2) and cryosurgery (n=1). At 2 to 14-year follow up, recurrences of skin cancer occurred in 3 (11.5 %) cases. Good aesthetic and functional results were observed. Conclusion. Cryo-radiotherapy was shown to be effective, providing long-term aesthetic and functional results. |
| first_indexed | 2024-04-10T01:53:32Z |
| format | Article |
| id | doaj.art-a34a56c8ea24403098ecf296e30e65fc |
| institution | Directory Open Access Journal |
| issn | 1814-4861 2312-3168 |
| language | Russian |
| last_indexed | 2025-03-14T10:09:13Z |
| publishDate | 2017-12-01 |
| publisher | Russian Academy of Sciences, Tomsk National Research Medical Center |
| record_format | Article |
| series | Сибирский онкологический журнал |
| spelling | doaj.art-a34a56c8ea24403098ecf296e30e65fc2025-03-02T11:16:09ZrusRussian Academy of Sciences, Tomsk National Research Medical CenterСибирский онкологический журнал1814-48612312-31682017-12-01166677210.21294/1814-4861-2017-16-6-67-72500CRYO-RADIOTHERAPY FOR LOCAL LYADVANCED RECURRENT SKIN CANCER OF THE FACEI. N. Pustynskiy0T. D. Tabolinovskaya1S. I. Tkachev2S. B. Alieva3R. I. Azizian4E. V. Kiva5A. V. Egorova6S. B. Peterson7N.N. Blokhin National Medical Research Cancer Center, Moscow; N.I. Pirogov Russian National Research Medical University, MoscowN.N. Blokhin National Medical Research Cancer Center, MoscowN.N. Blokhin National Medical Research Cancer Center, MoscowN.N. Blokhin National Medical Research Cancer Center, MoscowN.N. Blokhin National Medical Research Cancer Center, MoscowN.I. Pirogov Russian National Research Medical University, MoscowN.I. Pirogov Russian National Research Medical University, MoscowN.I. Pirogov Russian National Research Medical University, MoscowThe aim of the study was to improve the treatment outcomes for patients with locally advanced recurrent basal cell and squamous cell skin carcinomas of the face. Material and methods. A total of 26 patients with locally advanced recurrent basal cell (n=21) and squamous cell (n=5) skin carcinomas of the skin were treated with radiotherapy (2–2.5 Gy daily fractions to a total dose of 60–70 Gy, 5 days a week) in combination with local freezing of the tumor. Local cooling of the tumor to the temperature of tissue freezing was performed 10–15 minutes before each session of radiation therapy using liquid nitrogen cryo-preservation equipment. Patients with recurrent skin cancer who had received previously radiation therapy were not eligible for cryoradiotherapy. Results. Complete response was achieved in 23 (88.5 %) patients, residual tumors were removed by conventional surgery (n=2) and cryosurgery (n=1). At 2 to 14-year follow up, recurrences of skin cancer occurred in 3 (11.5 %) cases. Good aesthetic and functional results were observed. Conclusion. Cryo-radiotherapy was shown to be effective, providing long-term aesthetic and functional results.https://www.siboncoj.ru/jour/article/view/643skin cancer of the facelocally-advanced recurrent tumorscryo-radiotherapy |
| spellingShingle | I. N. Pustynskiy T. D. Tabolinovskaya S. I. Tkachev S. B. Alieva R. I. Azizian E. V. Kiva A. V. Egorova S. B. Peterson CRYO-RADIOTHERAPY FOR LOCAL LYADVANCED RECURRENT SKIN CANCER OF THE FACE Сибирский онкологический журнал skin cancer of the face locally-advanced recurrent tumors cryo-radiotherapy |
| title | CRYO-RADIOTHERAPY FOR LOCAL LYADVANCED RECURRENT SKIN CANCER OF THE FACE |
| title_full | CRYO-RADIOTHERAPY FOR LOCAL LYADVANCED RECURRENT SKIN CANCER OF THE FACE |
| title_fullStr | CRYO-RADIOTHERAPY FOR LOCAL LYADVANCED RECURRENT SKIN CANCER OF THE FACE |
| title_full_unstemmed | CRYO-RADIOTHERAPY FOR LOCAL LYADVANCED RECURRENT SKIN CANCER OF THE FACE |
| title_short | CRYO-RADIOTHERAPY FOR LOCAL LYADVANCED RECURRENT SKIN CANCER OF THE FACE |
| title_sort | cryo radiotherapy for local lyadvanced recurrent skin cancer of the face |
| topic | skin cancer of the face locally-advanced recurrent tumors cryo-radiotherapy |
| url | https://www.siboncoj.ru/jour/article/view/643 |
| work_keys_str_mv | AT inpustynskiy cryoradiotherapyforlocallyadvancedrecurrentskincanceroftheface AT tdtabolinovskaya cryoradiotherapyforlocallyadvancedrecurrentskincanceroftheface AT sitkachev cryoradiotherapyforlocallyadvancedrecurrentskincanceroftheface AT sbalieva cryoradiotherapyforlocallyadvancedrecurrentskincanceroftheface AT riazizian cryoradiotherapyforlocallyadvancedrecurrentskincanceroftheface AT evkiva cryoradiotherapyforlocallyadvancedrecurrentskincanceroftheface AT avegorova cryoradiotherapyforlocallyadvancedrecurrentskincanceroftheface AT sbpeterson cryoradiotherapyforlocallyadvancedrecurrentskincanceroftheface |