The Role of BNCT in Breast Cancer Treatment
Boron neutron capture therapy (BNCT) is a promising future technique of breast cancer therapy. BNCT is a cell-targetting therapy. In BNCT, the use of boron-10 combined with curcumin analog will provide selective radiation therapy only to breast cancer cells, whereas healthy cells will not be affecte...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Center for Development of Nuclear Informatics, National Nuclear Energy Agency (BATAN)
2019-12-01
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| Series: | Atom Indonesia |
| Subjects: | |
| Online Access: | http://aij.batan.go.id/index.php/aij/article/view/936 |
| _version_ | 1818504933070077952 |
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| author | B. Poedjomartono Y. Sardjono E. Meiyanto H. Winarno |
| author_facet | B. Poedjomartono Y. Sardjono E. Meiyanto H. Winarno |
| author_sort | B. Poedjomartono |
| collection | DOAJ |
| description | Boron neutron capture therapy (BNCT) is a promising future technique of breast cancer therapy. BNCT is a cell-targetting therapy. In BNCT, the use of boron-10 combined with curcumin analog will provide selective radiation therapy only to breast cancer cells, whereas healthy cells will not be affected. This is because the alpha radiation from the boron-10 nuclei that fission due to thermal neutron irradiation only has a short range of between 4 and 9 μm, whereas the cell diameter is between 10and 20 μm, so the reaction is limited only to the cancer cells. If the development of BNCT succeeds, then in the future the malignancy of the breast cancer will be effectively treated by cancer-cell targeted therapy, thereby avoiding the side effects of conventional therapy. |
| first_indexed | 2024-12-10T21:43:54Z |
| format | Article |
| id | doaj.art-a34cfc1a13c4462d97b7c495dd6c4162 |
| institution | Directory Open Access Journal |
| issn | 0126-1568 |
| language | English |
| last_indexed | 2024-12-10T21:43:54Z |
| publishDate | 2019-12-01 |
| publisher | Center for Development of Nuclear Informatics, National Nuclear Energy Agency (BATAN) |
| record_format | Article |
| series | Atom Indonesia |
| spelling | doaj.art-a34cfc1a13c4462d97b7c495dd6c41622022-12-22T01:32:25ZengCenter for Development of Nuclear Informatics, National Nuclear Energy Agency (BATAN)Atom Indonesia0126-15682019-12-0145313914610.17146/aij.2019.936382The Role of BNCT in Breast Cancer TreatmentB. Poedjomartono0Y. Sardjono1E. Meiyanto2H. Winarno3Department of Radiology, Faculty of Medicine, University of Gadjah Mada, Jl. Farmako, Sekip Utara, Yogyakarta 55281, IndonesiaCenter for Accelerator Science and Technology, National Nuclear Energy Agency of Indonesia, Jl. Babarsari, Yogyakarta 55281, IndonesiaFaculty of Pharmacy, University of Gadjah Mada, Jl. Farmako, Sekip Utara, Yogyakarta 55281, IndonesiaCenter for Isotopes and Radiation Application, National Nuclear Energy Agency of Indonesia, Jl. Lebak Bulus Raya No. 49, Jakarta 12440, IndonesiaBoron neutron capture therapy (BNCT) is a promising future technique of breast cancer therapy. BNCT is a cell-targetting therapy. In BNCT, the use of boron-10 combined with curcumin analog will provide selective radiation therapy only to breast cancer cells, whereas healthy cells will not be affected. This is because the alpha radiation from the boron-10 nuclei that fission due to thermal neutron irradiation only has a short range of between 4 and 9 μm, whereas the cell diameter is between 10and 20 μm, so the reaction is limited only to the cancer cells. If the development of BNCT succeeds, then in the future the malignancy of the breast cancer will be effectively treated by cancer-cell targeted therapy, thereby avoiding the side effects of conventional therapy.http://aij.batan.go.id/index.php/aij/article/view/936bnctboron-10curcumin analoguebreast cancer |
| spellingShingle | B. Poedjomartono Y. Sardjono E. Meiyanto H. Winarno The Role of BNCT in Breast Cancer Treatment Atom Indonesia bnct boron-10 curcumin analogue breast cancer |
| title | The Role of BNCT in Breast Cancer Treatment |
| title_full | The Role of BNCT in Breast Cancer Treatment |
| title_fullStr | The Role of BNCT in Breast Cancer Treatment |
| title_full_unstemmed | The Role of BNCT in Breast Cancer Treatment |
| title_short | The Role of BNCT in Breast Cancer Treatment |
| title_sort | role of bnct in breast cancer treatment |
| topic | bnct boron-10 curcumin analogue breast cancer |
| url | http://aij.batan.go.id/index.php/aij/article/view/936 |
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