Functional interactions between neurofibromatosis tumor suppressors underlie Schwann cell tumor de-differentiation and treatment resistance

Functional interactions between neurofibromatosis tumor suppressors underlie Schwann cell tumor de-differentiation and treatment resistance

Abstract Schwann cell tumors are the most common cancers of the peripheral nervous system and can arise in patients with neurofibromatosis type-1 (NF-1) or neurofibromatosis type-2 (NF-2). Functional interactions between NF1 and NF2 and broader mechanisms underlying malignant transformation of the S...

Full description

Bibliographic Details
Main Authors: Harish N. Vasudevan, Emily Payne, Cyrille L. Delley, S. John Liu, Kanish Mirchia, Matthew J. Sale, Sydney Lastella, Maria Sacconi Nunez, Calixto-Hope G. Lucas, Charlotte D. Eaton, Tim Casey-Clyde, Stephen T. Magill, William C. Chen, Steve E. Braunstein, Arie Perry, Line Jacques, Alyssa T. Reddy, Melike Pekmezci, Adam R. Abate, Frank McCormick, David R. Raleigh
Format: Article
Language:English
Published: Nature Portfolio 2024-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-44755-9

Internet

https://doi.org/10.1038/s41467-024-44755-9

Similar Items