Influence of Inlet Boundary Conditions on the Prediction of Flow Field and Hemolysis in Blood Pumps Using Large-Eddy Simulation

Inlet boundary conditions (BC) are one of the uncertainties which may influence the prediction of flow field and hemolysis in blood pumps. This study investigated the influence of inlet BC, including the length of inlet pipe, type of inlet BC (mass flow rate or experimental velocity profile) and tur...

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Main Authors: Wen-Jing Xiang, Jia-Dong Huo, Wei-Tao Wu, Peng Wu
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Bioengineering
Subjects:
Online Access:https://www.mdpi.com/2306-5354/10/2/274
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author Wen-Jing Xiang
Jia-Dong Huo
Wei-Tao Wu
Peng Wu
author_facet Wen-Jing Xiang
Jia-Dong Huo
Wei-Tao Wu
Peng Wu
author_sort Wen-Jing Xiang
collection DOAJ
description Inlet boundary conditions (BC) are one of the uncertainties which may influence the prediction of flow field and hemolysis in blood pumps. This study investigated the influence of inlet BC, including the length of inlet pipe, type of inlet BC (mass flow rate or experimental velocity profile) and turbulent intensity (no perturbation, 5%, 10%, 20%) on the prediction of flow field and hemolysis of a benchmark centrifugal blood pump (the FDA blood pump) and a commercial axial blood pump (Heartmate II), using large-eddy simulation. The results show that the influence of boundary conditions on integral pump performance metrics, including pressure head and hemolysis, is negligible. The influence on local flow structures, such as velocity distributions, mainly existed in the inlet. For the centrifugal FDA blood pump, the influence of type of inlet BC and inlet position on velocity distributions can also be observed at the diffuser. Overall, the effects of position of inlet and type of inlet BC need to be considered if local flow structures are the focus, while the influence of turbulent intensity is negligible and need not be accounted for during numerical simulations of blood pumps.
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spelling doaj.art-a3520fdadb1c46109ddc3a5b2d5300582023-11-16T19:12:07ZengMDPI AGBioengineering2306-53542023-02-0110227410.3390/bioengineering10020274Influence of Inlet Boundary Conditions on the Prediction of Flow Field and Hemolysis in Blood Pumps Using Large-Eddy SimulationWen-Jing Xiang0Jia-Dong Huo1Wei-Tao Wu2Peng Wu3Artificial Organ Technology Laboratory, School of Mechanical and Electric Engineering, Soochow University, Suzhou 215000, ChinaArtificial Organ Technology Laboratory, School of Mechanical and Electric Engineering, Soochow University, Suzhou 215000, ChinaSchool of Mechanical Engineering, Nanjing University of Science and Technology, Nanjing 210095, ChinaArtificial Organ Technology Laboratory, School of Mechanical and Electric Engineering, Soochow University, Suzhou 215000, ChinaInlet boundary conditions (BC) are one of the uncertainties which may influence the prediction of flow field and hemolysis in blood pumps. This study investigated the influence of inlet BC, including the length of inlet pipe, type of inlet BC (mass flow rate or experimental velocity profile) and turbulent intensity (no perturbation, 5%, 10%, 20%) on the prediction of flow field and hemolysis of a benchmark centrifugal blood pump (the FDA blood pump) and a commercial axial blood pump (Heartmate II), using large-eddy simulation. The results show that the influence of boundary conditions on integral pump performance metrics, including pressure head and hemolysis, is negligible. The influence on local flow structures, such as velocity distributions, mainly existed in the inlet. For the centrifugal FDA blood pump, the influence of type of inlet BC and inlet position on velocity distributions can also be observed at the diffuser. Overall, the effects of position of inlet and type of inlet BC need to be considered if local flow structures are the focus, while the influence of turbulent intensity is negligible and need not be accounted for during numerical simulations of blood pumps.https://www.mdpi.com/2306-5354/10/2/274blood pumpflow fieldhemolysisinlet boundary conditionturbulent intensityCFD
spellingShingle Wen-Jing Xiang
Jia-Dong Huo
Wei-Tao Wu
Peng Wu
Influence of Inlet Boundary Conditions on the Prediction of Flow Field and Hemolysis in Blood Pumps Using Large-Eddy Simulation
Bioengineering
blood pump
flow field
hemolysis
inlet boundary condition
turbulent intensity
CFD
title Influence of Inlet Boundary Conditions on the Prediction of Flow Field and Hemolysis in Blood Pumps Using Large-Eddy Simulation
title_full Influence of Inlet Boundary Conditions on the Prediction of Flow Field and Hemolysis in Blood Pumps Using Large-Eddy Simulation
title_fullStr Influence of Inlet Boundary Conditions on the Prediction of Flow Field and Hemolysis in Blood Pumps Using Large-Eddy Simulation
title_full_unstemmed Influence of Inlet Boundary Conditions on the Prediction of Flow Field and Hemolysis in Blood Pumps Using Large-Eddy Simulation
title_short Influence of Inlet Boundary Conditions on the Prediction of Flow Field and Hemolysis in Blood Pumps Using Large-Eddy Simulation
title_sort influence of inlet boundary conditions on the prediction of flow field and hemolysis in blood pumps using large eddy simulation
topic blood pump
flow field
hemolysis
inlet boundary condition
turbulent intensity
CFD
url https://www.mdpi.com/2306-5354/10/2/274
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AT jiadonghuo influenceofinletboundaryconditionsonthepredictionofflowfieldandhemolysisinbloodpumpsusinglargeeddysimulation
AT weitaowu influenceofinletboundaryconditionsonthepredictionofflowfieldandhemolysisinbloodpumpsusinglargeeddysimulation
AT pengwu influenceofinletboundaryconditionsonthepredictionofflowfieldandhemolysisinbloodpumpsusinglargeeddysimulation