Analytical Methods for Determination of Ketoprofen Drug: A review
Ketoprofen has recently been proven to offer therapeutic potential in preventing cancers such as colorectal and lung tumors, as well as in treating neurological illnesses. The goal of this review is to show the methods that have been used for determining ketoprofen in pharmaceutical formulations. P...
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| Format: | Article |
| Language: | English |
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University of Baghdad
2022-07-01
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| Series: | Ibn Al-Haitham Journal for Pure and Applied Sciences |
| Subjects: | |
| Online Access: | https://jih.uobaghdad.edu.iq/index.php/j/article/view/2842 |
| _version_ | 1828182294207135744 |
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| author | Jasim Shamar Sumayha Abbas Zahra Abbas |
| author_facet | Jasim Shamar Sumayha Abbas Zahra Abbas |
| author_sort | Jasim Shamar |
| collection | DOAJ |
| description |
Ketoprofen has recently been proven to offer therapeutic potential in preventing cancers such as colorectal and lung tumors, as well as in treating neurological illnesses. The goal of this review is to show the methods that have been used for determining ketoprofen in pharmaceutical formulations. Precision product quality control is crucial to confirm the composition of the drugs in pharmaceutical use. Several analytical techniques, including chromatographic and spectroscopic methods, have been used for determining ketoprofen in different sample forms such as a tablet, capsule, ampoule, gel, and human plasma. The limit of detection of ketoprofen was 0.1 ng/ ml using liquid chromatography with tandem mass spectrometry, while it was 0.01- 0.30 µg/ ml using high performance liquid chromatography and 0.00004 - 0.436 µg/ ml, 0.82 µg/ ml, 1.0 µg/ ml, 10 µg/ ml and 208.5 - 237.6 µg/ ml using flow injection, electrokinetic chromatography, capillary electrophoresis, gas chromatography-flame ionisation detection and derivative infrared spectroscopy respectively.
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| first_indexed | 2024-04-12T06:15:07Z |
| format | Article |
| id | doaj.art-a35325f07b6f40ec9e480b6a9df1a511 |
| institution | Directory Open Access Journal |
| issn | 1609-4042 2521-3407 |
| language | English |
| last_indexed | 2024-04-12T06:15:07Z |
| publishDate | 2022-07-01 |
| publisher | University of Baghdad |
| record_format | Article |
| series | Ibn Al-Haitham Journal for Pure and Applied Sciences |
| spelling | doaj.art-a35325f07b6f40ec9e480b6a9df1a5112022-12-22T03:44:31ZengUniversity of BaghdadIbn Al-Haitham Journal for Pure and Applied Sciences1609-40422521-34072022-07-0135310.30526/35.3.2842Analytical Methods for Determination of Ketoprofen Drug: A reviewJasim Shamar0Sumayha Abbas1Zahra Abbas2Department of Chemistry, College of Education for Pure Science \ Ibn Al-Haitham, Universityof Baghdad, Baghdad, Iraq.Department of Chemistry, College of Education for Pure Science \ Ibn Al-Haitham, Universityof Baghdad, Baghdad, Iraq.Department of Chemistry, College of Education for Pure Science \ Ibn Al-Haitham, Universityof Baghdad, Baghdad, Iraq. Ketoprofen has recently been proven to offer therapeutic potential in preventing cancers such as colorectal and lung tumors, as well as in treating neurological illnesses. The goal of this review is to show the methods that have been used for determining ketoprofen in pharmaceutical formulations. Precision product quality control is crucial to confirm the composition of the drugs in pharmaceutical use. Several analytical techniques, including chromatographic and spectroscopic methods, have been used for determining ketoprofen in different sample forms such as a tablet, capsule, ampoule, gel, and human plasma. The limit of detection of ketoprofen was 0.1 ng/ ml using liquid chromatography with tandem mass spectrometry, while it was 0.01- 0.30 µg/ ml using high performance liquid chromatography and 0.00004 - 0.436 µg/ ml, 0.82 µg/ ml, 1.0 µg/ ml, 10 µg/ ml and 208.5 - 237.6 µg/ ml using flow injection, electrokinetic chromatography, capillary electrophoresis, gas chromatography-flame ionisation detection and derivative infrared spectroscopy respectively. https://jih.uobaghdad.edu.iq/index.php/j/article/view/2842Analytical Methods, Ketoprofen, Non-steroidal anti-inflammatory drugs |
| spellingShingle | Jasim Shamar Sumayha Abbas Zahra Abbas Analytical Methods for Determination of Ketoprofen Drug: A review Ibn Al-Haitham Journal for Pure and Applied Sciences Analytical Methods, Ketoprofen, Non-steroidal anti-inflammatory drugs |
| title | Analytical Methods for Determination of Ketoprofen Drug: A review |
| title_full | Analytical Methods for Determination of Ketoprofen Drug: A review |
| title_fullStr | Analytical Methods for Determination of Ketoprofen Drug: A review |
| title_full_unstemmed | Analytical Methods for Determination of Ketoprofen Drug: A review |
| title_short | Analytical Methods for Determination of Ketoprofen Drug: A review |
| title_sort | analytical methods for determination of ketoprofen drug a review |
| topic | Analytical Methods, Ketoprofen, Non-steroidal anti-inflammatory drugs |
| url | https://jih.uobaghdad.edu.iq/index.php/j/article/view/2842 |
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